New drug cocktail aims to shrink Hard-to-Treat breast tumors

NCT ID NCT07389733

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests an experimental drug called HRS-6208 combined with other cancer drugs (HRS-8080, fulvestrant, or letrozole) in 180 adults with advanced breast cancer that cannot be removed by surgery or has spread. The main goals are to find safe doses and see if the combination shrinks tumors. Participants will be monitored for side effects and how long the cancer stays under control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

HRS-6208 (an experimental drug) combined with other drugs like HRS-8080, fulvestrant, or letrozole

What this could lead to

If successful, this could lead to a new treatment option for people with advanced breast cancer that has stopped responding to standard therapies.

What could go wrong

This is an early-phase trial with only 180 participants, so the drugs may not work as hoped or could cause unexpected side effects. Results may not apply to all breast cancer patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Second Affiliated Hospital of Dalian Medical University

    RECRUITING

    Dalian, Liaoning, 116031, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • West China Hospital, Sichuan University

    RECRUITING

    Chengdu, Sichuan, 610044, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact