New knee pain drug enters early human testing

NCT ID NCT07351968

First seen Jan 20, 2026 · Last updated May 14, 2026 · Updated 18 times

Summary

This early-stage study tests an experimental drug called HRS-2129 in 200 people with moderate to severe knee osteoarthritis pain. The goal is to see if different doses can reduce pain and improve knee function compared to a placebo or an active control. Participants must stop other pain treatments during the study, except for acetaminophen as a rescue medication.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Drum Tower Hospital affiliated to Nanjing University School of Medicine

    RECRUITING

    Nanjing, Jiangsu, 210005, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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