Triple threat: HPV vaccine plus immunotherapy shows promise against head and neck cancer

NCT ID NCT04369937

First seen Nov 01, 2025 · Last updated Jun 14, 2026 · Updated 30 times

Summary

This study tested a new treatment for a type of head and neck cancer linked to HPV-16. The treatment combined an HPV vaccine (ISA101b), an immunotherapy drug (pembrolizumab), and standard chemo-radiation. The goal was to see if this mix could help control the cancer for longer. The study involved 18 patients with intermediate-risk disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • UPMC Hillman Cancer Center

    Pittsburgh, Pennsylvania, 15232, United States

Conditions

Explore the condition pages connected to this study.