Can a tiny ear zap unlock your body's own painkillers?

NCT ID NCT05490134

First seen Jan 09, 2026 · Last updated Jun 15, 2026 · Updated 21 times

Summary

This study tests whether a nerve stimulation device placed on the ear (tAN) reduces pain by causing the body to release its own natural painkillers (opioids). Healthy adults aged 18-65 will receive either real or sham stimulation while also getting a drug that blocks opioids or a placebo. The goal is to understand how tAN works, not to treat a disease.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Medical University of South Carolina

    RECRUITING

    Charleston, South Carolina, 29425, United States

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.