Supercharged immune cells take on incurable tumors in early trial

NCT ID NCT04520711

First seen Nov 19, 2025 · Last updated May 25, 2026 · Updated 25 times

Summary

This early-phase trial tests a new approach for people with incurable epithelial cancers. Patients receive specially engineered immune cells (TCR-T) that target unique markers on their tumors, plus two drugs that boost the immune response. The main goal is to check safety and find the right dose, while also tracking whether tumors shrink or stop growing. About 24 adults with advanced cancers that have not responded to standard treatments are taking part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Providence Portland Medical Center

    Portland, Oregon, 97213, United States

Conditions

Explore the condition pages connected to this study.