New combo therapy aims to wipe out prostate tumors before surgery
NCT ID NCT06834321
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This Phase 2 trial tests whether adding homoharringtonine, a drug from a plant, to standard hormone therapy can better shrink or eliminate prostate cancer before surgery. About 96 men with locally advanced or limited spread prostate cancer will receive either the drug combo or a placebo plus hormones. The main goal is to see if the tumor completely disappears or becomes very small in the removed prostate.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Homoharringtonine (a plant-derived drug) combined with androgen deprivation therapy (hormone therapy)
What this could lead to
If it works, this could lead to a more effective pre-surgery treatment that reduces or eliminates prostate tumors, potentially improving long-term outcomes.
What could go wrong
This is an early Phase 2 trial with only 96 participants, so results may not apply broadly. The drug can cause side effects like bone marrow suppression, and the combination may not prove better than standard therapy.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for PROSTATE CA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
The First People Hospital of Nantong City
RECRUITINGNantong, Jiangsu, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Zhongda Hospital
RECRUITINGNanjing, Jiangsu, China
Contact Phone: •••-•••-•••• Email: •••••@•••••