Could cancer patients with dangerous clots be treated at home?
NCT ID NCT07315347
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether people with active cancer who have a blood clot in their lungs (pulmonary embolism) can be safely treated at home instead of in the hospital. About 824 participants will be randomly assigned to either go home within 24 hours or stay in the hospital for at least 48 hours. The main goal is to see if home treatment is as good as hospital care at preventing new clots, major bleeding, or death within 14 days.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- home treatment (early discharge with phone follow-up) vs hospitalisation
- What this could lead to
- If successful, this could show that many cancer patients with a pulmonary embolism can be safely treated at home instead of in the hospital, improving comfort and reducing healthcare costs.
- What could go wrong
- This is a non-inferiority trial, so it aims to prove home care is not worse than hospital care, not that it is better. The results may not apply to all cancer patients, and there is a risk of bleeding or recurrent clots that could be harder to manage at home.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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C01 - Pneumologie et Soins Intensifs - HEGP
RECRUITINGParis, France, 75015, France
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C02 - Département interdisciplinaire d'organisation des parcours patients - Institut gustave Roussy
RECRUITINGVillejuif, France, 94805, France
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C03 - Médecine interne et médecine vasculaire - Hospices Civils de Lyon
RECRUITINGPierre-Bénite, France, 69310, France
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C04 - Oncologie Médicale - Centre Georges-François Leclerc - CLCC
NOT_YET_RECRUITINGDijon, France, 21079, France
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C05 - Médecine Interne - Hôpital Louis Mourier - APHP
RECRUITINGColombes, France, 92700, France
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C06 - Pneumologie - Hôpital Cochin - APHP
NOT_YET_RECRUITINGParis, France, 75014, France
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C07 - Médecine Vasculaire - Hôpital Saint Joseph
NOT_YET_RECRUITINGParis, 75014, France
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C08 - Département de Médecine interne et pneumologie - CHU la Cavale Blanche
RECRUITINGBrest, 29609, France
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C09 - Médecine vasculaire et thérapeuthique - CHU Saint Etienne
RECRUITINGSaint-Priest-en-Jarez, 42270, France
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C10 - Département médecine urgence - CHU Angers
RECRUITINGAngers, 49933, France
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C11 - Pneumologie - CH René Dubos
RECRUITINGCergy-Pontoise, 95304, France
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C12 - Médecine Vasculaire - CHU Amiens Picardie
RECRUITINGAmiens, 80054, France
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C13 - Médecine Vasculaire - CHU Dijon
NOT_YET_RECRUITINGDijon, 21000, France
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C14 - Médecine Vasculaire - CH Toulon
RECRUITINGToulon, 83100, France
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C15 - Médecine Interne - CHU Rouen
RECRUITINGRouen, 76031, France
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C16 - Département Urgences - CHU Clermont Ferrand
RECRUITINGClermont-Ferrand, 63000, France
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C17 - Médecine Interne - CHU Nantes
RECRUITINGNantes, 44000, France
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C18 - Pneumologie - CH de Versailles Hôpital André Mignot
RECRUITINGLe Chesnay, 78157, France
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C19 - Pneumologie - Hôpital Foch
RECRUITINGSuresnes, 92151, France
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C20 - Médecine Vasculaire - CHU Toulouse
NOT_YET_RECRUITINGToulouse, 31059, France
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