Could cancer patients with dangerous clots be treated at home?

NCT ID NCT07315347

First seen Jan 10, 2026 · Last updated Jun 23, 2026 · Updated 20 times

Summary

This study looks at whether people with active cancer who have a blood clot in their lungs (pulmonary embolism) can be safely treated at home instead of in the hospital. About 824 participants will be randomly assigned to either go home within 24 hours or stay in the hospital for at least 48 hours. The main goal is to see if home treatment is as good as hospital care at preventing new clots, major bleeding, or death within 14 days.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • C01 - Pneumologie et Soins Intensifs - HEGP

    RECRUITING

    Paris, France, 75015, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • C02 - Département interdisciplinaire d'organisation des parcours patients - Institut gustave Roussy

    RECRUITING

    Villejuif, France, 94805, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • C03 - Médecine interne et médecine vasculaire - Hospices Civils de Lyon

    RECRUITING

    Pierre-Bénite, France, 69310, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • C04 - Oncologie Médicale - Centre Georges-François Leclerc - CLCC

    NOT_YET_RECRUITING

    Dijon, France, 21079, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • C05 - Médecine Interne - Hôpital Louis Mourier - APHP

    RECRUITING

    Colombes, France, 92700, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • C06 - Pneumologie - Hôpital Cochin - APHP

    NOT_YET_RECRUITING

    Paris, France, 75014, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • C07 - Médecine Vasculaire - Hôpital Saint Joseph

    NOT_YET_RECRUITING

    Paris, 75014, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • C08 - Département de Médecine interne et pneumologie - CHU la Cavale Blanche

    RECRUITING

    Brest, 29609, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • C09 - Médecine vasculaire et thérapeuthique - CHU Saint Etienne

    RECRUITING

    Saint-Priest-en-Jarez, 42270, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • C10 - Département médecine urgence - CHU Angers

    RECRUITING

    Angers, 49933, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • C11 - Pneumologie - CH René Dubos

    RECRUITING

    Cergy-Pontoise, 95304, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • C12 - Médecine Vasculaire - CHU Amiens Picardie

    RECRUITING

    Amiens, 80054, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • C13 - Médecine Vasculaire - CHU Dijon

    NOT_YET_RECRUITING

    Dijon, 21000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • C14 - Médecine Vasculaire - CH Toulon

    RECRUITING

    Toulon, 83100, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • C15 - Médecine Interne - CHU Rouen

    RECRUITING

    Rouen, 76031, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • C16 - Département Urgences - CHU Clermont Ferrand

    RECRUITING

    Clermont-Ferrand, 63000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • C17 - Médecine Interne - CHU Nantes

    RECRUITING

    Nantes, 44000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • C18 - Pneumologie - CH de Versailles Hôpital André Mignot

    RECRUITING

    Le Chesnay, 78157, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • C19 - Pneumologie - Hôpital Foch

    RECRUITING

    Suresnes, 92151, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • C20 - Médecine Vasculaire - CHU Toulouse

    NOT_YET_RECRUITING

    Toulouse, 31059, France

    Contact Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

home treatment (early discharge with phone follow-up) vs hospitalisation

What this could lead to

If successful, this could show that many cancer patients with a pulmonary embolism can be safely treated at home instead of in the hospital, improving comfort and reducing healthcare costs.

What could go wrong

This is a non-inferiority trial, so it aims to prove home care is not worse than hospital care, not that it is better. The results may not apply to all cancer patients, and there is a risk of bleeding or recurrent clots that could be harder to manage at home.

Conditions

The condition(s) this trial relates to.

pulmonary embolism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.