Experimental lymphoma pill shows promise but trial halted early

NCT ID NCT03779113

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 27 times

Summary

This early-stage study tested an oral drug called HMPL-523 in 69 adults with lymphoma that had returned or stopped responding to standard treatments. The goal was to check the drug's safety and find the right dose. The trial was stopped early, but researchers looked at side effects and how well the drug worked in some patients.

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Contacts and locations

Locations

  • Aarhus University Hospital

    Aarhus, Denmark

  • Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII (Presidio Papa Giovanni XXIII)

    Bergamo, Bergamo, 24127, Italy

  • Azienda Socio Sanitaria Territoriale di Monza (Presidio San Gerardo)

    Monza, Italy

  • CHU Clermont Ferrand - Hôpital d'Estaing

    Clermont-Ferrand, France

  • CHU Poitiers - Hôpital la Milétrie

    Poitiers, France

  • Clinical Research Alliance

    New Hyde Park, New York, 11042, United States

  • Fundacion Jimenez Diaz

    Madrid, Spain

  • Groupe Hospitalier Pitie-Salpetriere

    Paris, France

  • Helsingin yliopistollinen keskussairaala

    Helsinki, 00029, Finland

  • Hospital Universitari Vall d'Hebron

    Barcelona, Spain

  • Hospital Universitario Infanta Leonor

    Madrid, Spain

  • Hospital Universitario Quironsalud Madrid

    Madrid, Spain

  • Hospital Universitario Ramon y Cajal

    Madrid, 28034, Spain

  • Hospital Universitario Virgen Macarena

    Seville, Spain

  • Hospital Universitario Virgen del Rocio

    Seville, Spain

  • Hôpital Henri Mondor

    Créteil, France

  • ICO Badalona - Hospital Universitari Germans Trias i Pujol

    Barcelona, Spain

  • Innovative Clinical Research Institute

    Downey, California, 90241, United States

  • Institut Català d'Oncologia

    Barcelona, Spain

  • KO-MED Centra Kliniczne

    Biała Podlaska, Poland

  • Leo Jenkins Cancer Center/ECU School of Medicine

    Greenville, North Carolina, 27834, United States

  • MD Anderson Cancer Centre

    Madrid, Spain

  • Nasz Lekarz Przychodnie Medyczne

    Torun, Poland

  • Ospedale San Raffaele

    Milan, Milano, 20132, Italy

  • Pacific Cancer Medical Center, Inc.

    Anaheim, California, 92801, United States

  • Renovatio Clinical

    The Woodlands, Texas, 77380, United States

  • Summit Medical Group

    Florham Park, New Jersey, 07932, United States

  • Tampereen yliopistollinen sairaala

    Tampere, 33520, Finland

  • The University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Uniwersytecki Szpital Kliniczny im. Jana Mikulicza Radeckiego

    Wroclaw, 50566, Poland

  • Uniwersyteckie Centrum Kliniczne

    Gdansk, Poland

  • Ventura County Hematology-Oncology Specialists

    Oxnard, California, 93030, United States

Conditions

Explore the condition pages connected to this study.