New hope for bleeding disorder: first human trial of HMB-002 begins
NCT ID NCT06754852
First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 2 times
Summary
This study tests a new medicine, HMB-002, in about 108 adults with von Willebrand disease (types 1 and 2). The goal is to check safety, how the drug moves in the body, and whether it helps control bleeding. It is the first time this drug is being tested in humans, starting with single doses and then repeated doses.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Arkansas Children's Hospital
NOT_YET_RECRUITINGLittle Rock, Arkansas, 72202, United States
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Basingstoke and North Hampshire Hospital
RECRUITINGBasingstoke, Hampshire, RG24 9NA, United Kingdom
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Children's Hospital of Los Angeles
NOT_YET_RECRUITINGLos Angeles, California, 90027, United States
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Emory Children's Center
NOT_YET_RECRUITINGAtlanta, Georgia, 30329, United States
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Fiona Stanley Hospital
NOT_YET_RECRUITINGMurdoch, Perth, WA 6150, Australia
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Hemophilia Center of Western Pennsylvania
NOT_YET_RECRUITINGPittsburgh, Pennsylvania, 15213, United States
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Innovative Hematology, Inc./Indiana Hemophilia and Thrombosis Center
RECRUITINGIndianapolis, Indiana, 46260, United States
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Mayo Clinic - Rochester
NOT_YET_RECRUITINGRochester, Minnesota, 55905, United States
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Oregon Health & Science University
NOT_YET_RECRUITINGPortland, Oregon, 97239, United States
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Phoenix Children's Hospital
NOT_YET_RECRUITINGPhoenix, Arizona, 85016, United States
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Richmond Pharmacology
RECRUITINGLondon, SE1 1YR, United Kingdom
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Royal Liverpool and Broadgreen University Hospitals NHS TRUST, The Roald Dahl Haemostasis and Thrombosis Centre
NOT_YET_RECRUITINGLiverpool, L7 8XP, United Kingdom
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Royal London Hospital
NOT_YET_RECRUITINGWhitechapel, London, E1 1FR, United Kingdom
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Royal Prince Alfred Hospital
RECRUITINGCamperdown, Sydney, NSW 2050, Australia
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St George's Hospital
NOT_YET_RECRUITINGTooting, London, SW17 0QT, United Kingdom
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St James's University Hospital, Leeds Haemophilia Centre
NOT_YET_RECRUITINGLeeds, LS9 7TF, United Kingdom
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St Thomas' Hospital
NOT_YET_RECRUITINGLondon, SE1 7EH, United Kingdom
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The Alfred Hospital
RECRUITINGMelbourne, Victoria, VIC 3004, Australia
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The University of Texas Southwestern Medical Center
NOT_YET_RECRUITINGDallas, Texas, 75390, United States
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Tulane University School of Medicine
NOT_YET_RECRUITINGNew Orleans, Louisiana, 70112, United States
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University Hospital of Wales
RECRUITINGCardiff, CF14 4XW, United Kingdom
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University Hospitals Birmingham NHS Foundation Trust
NOT_YET_RECRUITINGBirmingham, B15 2TH, United Kingdom
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University of Miami Hospital and Clinics, Sylvester Comprehensive Cancer Center
NOT_YET_RECRUITINGMiami, Florida, 33136, United States
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University of Michigan Hospitals, Department of Hemophilia and Coagulation Disorders
NOT_YET_RECRUITINGAnn Arbor, Michigan, 48109, United States
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Washington Institute For Coagulation (WIC)
NOT_YET_RECRUITINGSeattle, Washington, 98101, United States