New approach aims to tame rogue immune attack with fewer side effects

NCT ID NCT06160791

Summary

This study is testing a new treatment combination for adults newly diagnosed with hemophagocytic lymphohistiocytosis (HLH), a rare and severe condition where the immune system attacks the body. Researchers want to see if adding the drug ruxolitinib to a reduced-dose version of standard HLH therapy can effectively control the disease while causing fewer side effects. The study will enroll 36 adults to evaluate how well the combination works and how safe it is.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of California, Irvine

    RECRUITING

    Irvine, California, 92697, United States

    Contact

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • University of California, San Francisco

    RECRUITING

    San Francisco, California, 94143, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.