Engineered immune cells take aim at Hard-to-Treat cancers

NCT ID NCT05672459

First seen Jan 30, 2026 · Last updated Apr 25, 2026 · Updated 10 times

Summary

This early-stage trial tests a new treatment called IVS-3001, which uses a patient's own immune cells (CAR-T cells) that are modified to recognize and attack a protein called HLA-G found on some solid tumors. The study includes 31 adults with advanced solid tumors that have not responded to standard treatments. The main goals are to check the safety of the therapy and see if it can shrink tumors.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.