Simpler HIV treatment for kids tested in global trial
NCT ID NCT04337450
Summary
This study is testing whether a two-drug HIV treatment (dolutegravir/lamivudine) is as safe and effective as standard three-drug treatments for children aged 2-15 who already have their virus under control. About 370 children will be randomly assigned to either continue their current treatment or switch to the two-drug combination, taken once daily. Researchers will monitor the children's health and virus levels for at least 96 weeks to see if the simpler treatment works just as well.
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Contacts and locations
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Locations
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Baylor
Kampala, Uganda
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Birmingham Heartlands Hospital
Birmingham, United Kingdom
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Chiangrai Prachanukroh Hospital
Chiang Rai, Thailand
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Great Ormand Street Hospital
London, United Kingdom
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Hospital Universitario 12 de Octubre
Madrid, Spain
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Joint Clinical Research Centre
Kampala, Uganda
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Khon Kaen Hospital
Khon Kaen, Thailand
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King Edward VIII Hospital
Durban, South Africa
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MUJHU
Kampala, Uganda
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Nakornping Hospital
Chiang Mai, Thailand
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PHRU
Soweto, South Africa
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PHRU Klerksdorp
Klerksdorp, South Africa
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Prapokklao Hospital
Chanthaburi, Thailand
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St. Mary's Hospital
London, United Kingdom
Conditions
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