HIV-Fighting cells show promise in lymphoma treatment

NCT ID NCT04975698

First seen Jun 27, 2026 · Last updated Jun 30, 2026 · Updated 2 times

Summary

This study tested a new approach for people with both HIV and lymphoma. After high-dose chemotherapy and a stem cell transplant, participants received specially grown HIV-fighting immune cells (HST-NEETs). The goal was to see if giving these cells was feasible and if they could reduce the amount of hidden HIV in the body. The trial involved 12 participants and was completed.

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Conditions

The condition(s) this trial relates to.

Burkitt lymphoma classic Hodgkin lymphoma composite lymphoma diffuse large B-cell lymphoma high grade B-cell lymphoma HIV-associated cancer large-cell immunoblastic lymphoma plasmablastic lymphoma primary effusion lymphoma primary mediastinal large B-cell lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Baylor College of Medicine

    Houston, Texas, 77030, United States

  • City of Hope National Medical Center

    Duarte, California, 91010, United States

  • Georgetown

    Washington D.C., District of Columbia, 20057, United States

  • H. Lee Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • Icahn School of Medicine at Mount Sinai

    New York, New York, 10029, United States

  • Johns Hopkins University

    Baltimore, Maryland, 21231, United States

  • MD Anderson

    Houston, Texas, 77030, United States

  • Memorial Sloan Kettering (MSKCC)

    New York, New York, 10065, United States

  • Northside

    Atlanta, Georgia, 30342, United States

  • University of Illinois

    Chicago, Illinois, 60612, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States