HIV-Fighting cells show promise in lymphoma treatment

NCT ID NCT04975698

Completed Disease control Sponsor: Catherine Bollard Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 30, 2026 · Updated 2 times

Summary

This study tested a new approach for people with both HIV and lymphoma. After high-dose chemotherapy and a stem cell transplant, participants received specially grown HIV-fighting immune cells (HST-NEETs). The goal was to see if giving these cells was feasible and if they could reduce the amount of hidden HIV in the body. The trial involved 12 participants and was completed.

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Conditions

The condition(s) this trial relates to.

Burkitt lymphoma classic Hodgkin lymphoma composite lymphoma diffuse large B-cell lymphoma high grade B-cell lymphoma HIV-associated cancer large-cell immunoblastic lymphoma plasmablastic lymphoma primary effusion lymphoma primary mediastinal large B-cell lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV ASSOCIATED LYMPHOMA

Contacts and locations

Locations

Baylor College of Medicine

Houston, Texas, 77030, United States
City of Hope National Medical Center

Duarte, California, 91010, United States
Georgetown

Washington D.C., District of Columbia, 20057, United States
H. Lee Moffitt Cancer Center

Tampa, Florida, 33612, United States
Icahn School of Medicine at Mount Sinai

New York, New York, 10029, United States
Johns Hopkins University

Baltimore, Maryland, 21231, United States
MD Anderson

Houston, Texas, 77030, United States
Memorial Sloan Kettering (MSKCC)

New York, New York, 10065, United States
Northside

Atlanta, Georgia, 30342, United States
University of Illinois

Chicago, Illinois, 60612, United States
University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States

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