HIV switch study finds two drug combos equally effective

NCT ID NCT00931463

Completed Disease control Sponsor: Kirby Institute Source: ClinicalTrials.gov ↗

First seen Apr 09, 2026 · Last updated May 13, 2026 · Updated 6 times

Summary

This study looked at 558 people with HIV whose first treatment was no longer controlling the virus. Researchers compared two different second-line drug combinations: one with standard HIV drugs plus a booster, and another with a newer integrase inhibitor. After 48 weeks, both approaches worked equally well at suppressing HIV to very low levels. The goal was to find safe and effective options for people who need to switch treatments.

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Contacts and locations

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Locations

Albion Street Centre

Sydney, New South Wales, 2010, Australia
Auckland Hospital

Grafton, Auckland, 1, New Zealand
CAICI

Buenos Aires, Rosario Provincia de Sante Fe, 2000, Argentina
Centre Clinic

Melbourne, Victoria, 3182, Australia
Chelsea and Westminster Hospital

Fulham, London, SW10 9NH, United Kingdom
Chris Hani Baragwanath Hospital

Soweto, South Africa
Desmond Tutu HIV Foundation

Cape Town, South Africa
Evangel Hospital (ECWA)

Jos, Plateau State, Nigeria
FUNCEI

Buenos Aires, Argentina
Hopital Saint-Louis

Paris, France
Hospital Almenara

Lima, Peru
Hospital Central

Mendoza, 5500, Argentina
Hospital General de Agudos 'Teodoro Alvarez'

Buenos Aires, 1406, Argentina
Hospital General de Guadalajara

Guadalajara, Mexico
Hospital General de Leon

León, Mexico
Hospital Interzonal General de Agudos, Oscar Alende

Buenos Aires, Mar Del Plata Provincia, 1900, Argentina
Hospital Italiano

Buenos Aires, Argentina
Hospital J.M. Ramos Mejia

Buenos Aires, Argentina
Hospital Pelau Pinang

Kuala Lumpur, Malaysia
Hospital Prof. Alejandro Posadas

Buenos Aires, Argentina
Hospital Rawson

Córdoba, Argentina
Hospital San Borja-Arriaran

Santiago, Chile
Hospital Sungai Buloh

Kuala Lumpur, Malaysia
Hospital de Infecciosas FJ Muniz

Buenos Aires, Argentina
Hospital de la Universidad Catolica Pontificia

Santiago, Chile
IMPACTA/Hospital Dos de Mayo

Lima, Peru
Institute of Infectious Diseases

Pune, Pune, India
Instituto Nacional de Ciencias Medicas y Nutricion "Salvado Zubiran"

Mexico City, Mexico
Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia

Lima, Peru
J W Goethe Universitat

Frankfurt, Germany
Jos University Teaching Hospital (JUTH)

Jos, Plateau State, Nigeria
Josha Research

Bloemfontein, South Africa
Liverpool Hospital

Liverpool, New South Wales, 2170, Australia
Mater Misericordiae-Dublin

Dublin, Ireland
Medical Group Practice

Berlin, Germany
National Taiwan University Hospital

Taipei, Taiwan
Plateau State Specialist Hospital

Jos, Plateau State, Nigeria
Queen Elizabeth Hospital

Hong Kong, Kowloon, Hong Kong
St Vincent's Hospital

Sydney, New South Wales, 2010, Australia
Tan Tock Seng Hospital

Singapore, 308433, Singapore
The Alfred Hospital

Melbourne, Victoria, 3004, Australia
University of Malaysia

Kuala Lumpur, Malaysia
Via Libre

Lima, Peru
YRG Care

Chennai, India

Conditions

Explore the condition pages connected to this study.

HIV INFECTIONS