New drug cocktail aims to rescue HIV patients when other treatments fail

NCT ID NCT00196625

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a combination of three HIV drugs (amprenavir, lopinavir, and ritonavir) in patients whose current treatments are no longer working. The goal is to see if this new mix can lower the amount of HIV in the blood over 26 weeks. Participants are HIV-positive adults who have tried multiple previous therapies without success. The study compares two different doses of ritonavir to find the safest and most effective option.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

amprenavir, lopinavir, and ritonavir

What this could lead to

If successful, this combination could offer a new treatment option for people with HIV who have not responded to other therapies.

What could go wrong

This is a Phase 2 trial with only 100 participants, so results may not apply to everyone. The drugs can cause side effects and may not work for all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Service des Maladies Infectieuses et Tropicales, Hôpital Saint-Antoine

    Paris, France