Brotherly advice: sibling talks may boost HIV prevention

NCT ID NCT05805306

Completed Prevention Sponsor: Charles Drew University of Medicine and Science Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether training siblings to talk about HIV PrEP helps Latino men who have sex with men start taking it. 288 participants were split into two groups: one where siblings learned to discuss PrEP, and another where siblings discussed vaccines instead. The goal was to see if the PrEP conversations led more men to begin using PrEP.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: sibling-led PrEP promotion conversations
What this could lead to: If successful, this approach could offer a new way to increase HIV PrEP use among young Latino men, potentially reducing HIV infections in this community.
What could go wrong: This is a completed behavioral study, not a drug trial. The outcome depends on whether sibling conversations actually change behavior, which may not work for everyone.

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Conditions

The condition(s) this trial relates to.

Homosexuality HIV infectious disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV INFECTIONS

Contacts and locations

Locations

Charles R. Drew University of Medicine and Science

Los Angeles, California, 90059, United States

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