New vaginal insert could block HIV and herpes
NCT ID NCT06087913
First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 27 times
Summary
This study tested a vaginal insert containing two drugs (tenofovir alafenamide and elvitegravir) to see if it is safe and how it works in the body. The insert is designed to be used before sex to prevent HIV and herpes infection. 68 healthy women took part, using the insert daily for 3 days then every other day for 14 days. The goal was to check safety and drug levels, not to prove the insert prevents infection yet.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CAPRISA eThekwini Clinical Research Site
Durban, South Africa
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Eastern Virginia Medical School Clinical Research Clinic (EVMS CRC)
Norfolk, Virginia, 23507, United States
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Kenya Medical Research Institute (KEMRI)
Thika, Kenya
Conditions
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