HIV pill genvoya tested in teens and kids – could simplify treatment

NCT ID NCT01854775

Completed Disease control Sponsor: Gilead Sciences Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested the HIV medication Genvoya (a single daily pill) in 129 teenagers and children with HIV. The goal was to check how the drug is processed in the body, confirm the right dose, and see if it is safe. Participants included teens new to HIV treatment and children who already had the virus under control. The results help doctors know how to use this medicine in younger patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Genvoya (elvitegravir, cobicistat, emtricitabine, tenofovir alafenamide)
What this could lead to: If successful, this study helps confirm that Genvoya is safe and works well for treating HIV in teenagers and children, offering a simpler once-daily pill option.
What could go wrong: This is an early-to-mid stage study with a small number of participants (129). It focuses on dosing and short-term safety, not long-term outcomes. Side effects or lack of effectiveness in younger children are possible.

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Conditions

The condition(s) this trial relates to.

acquired immunodeficiency AIDS HIV infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACQUIRED IMMUNE DEFICIENCY SYNDROME (AIDS) HIV INFECTIONS

Contacts and locations

Locations

Be Part Yoluntu Centre

Cape Town, 7646, South Africa
Children's Research Institute

Washington D.C., District of Columbia, 20010, United States
Clinical HIV Research Unit

Johannesburg, 2041, South Africa
Department of Pediatrics, Faculty of Medicine, Khon Kaen University

Khon Kaen, 40002, Thailand
Desmond Tutu HIV Foundation

Cape Town, 7705, South Africa
Emory University School of Medicine

Atlanta, Georgia, 30322, United States
Empilweni Services and Research Unit (ESRU)

Johannesburg, 2092, South Africa
Joint Clinical Research Centre

Kampala, PO Box 10005, Uganda
KIDCRU Ward J8

Cape Town, 7505, South Africa
Miller's Children Hospital

Long Beach, California, 90806, United States
Perinatal HIV Research Unit Baragwanath Hospital

Johannesburg, 1862, South Africa
Queen Savang Vadhana Memorial Hospital

Chon Buri, 20110, Thailand
Seattle Children's Hospital

Seattle, Washington, 98105-0371, United States
St. Jude Children's Research Hospital

Memphis, Tennessee, 38105, United States
The HIV Netherlands Australia Thailand Research collaboration (HIV-NAT)

Bangkok, 10330, Thailand
University of Zimbabwe - Clinical Research Centre

Belgravia, 263, Zimbabwe

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