New daily pill aims to outperform standard HIV therapy in landmark trial

NCT ID NCT07711223

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This study tests a new experimental drug, ACC017, taken once daily alongside two other HIV medications (FTC/TAF), in adults with HIV-1 who have never been treated before. The goal is to see if ACC017 is as safe and effective as the current standard drug dolutegravir at lowering the amount of virus in the blood. Participants will be randomly assigned to receive either ACC017 or dolutegravir for 48 weeks, and then all will switch to ACC017 for another 48 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
an experimental drug called ACC017, taken as a tablet once daily, combined with emtricitabine/tenofovir alafenamide (FTC/TAF)
What this could lead to
If successful, ACC017 could offer a new once-daily treatment option for people starting HIV therapy, potentially with similar or better viral suppression than current standard care.
What could go wrong
This is an early-to-mid stage trial (Phase 1/2), so the drug's safety and effectiveness are not yet proven. It may not work as well as dolutegravir or could have unexpected side effects.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Ditan Hospital Capital Medical University, Beijing, China

    RECRUITING

    Beijing, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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