High-Protein diet may trigger cellular stress signals, small study hints
NCT ID NCT06621901
First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time
Summary
This study investigates whether eating a high-protein diet for 10 days changes levels of endoplasmic reticulum stress markers in the blood. Twenty healthy adults aged 19–45 with a normal BMI will follow a high-protein diet (about 30% of calories from protein) and later a normal-protein diet as a control. Researchers will measure stress-related proteins such as GRP78, PERK, Nrf2, and GPx-1 to better understand the short-term cellular effects of high protein intake.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- high protein diet (30% of total energy from protein) for 10 days, compared with a normal protein diet for 10 days
- What this could lead to
- If this trial yields clear results, it could help explain how high protein diets affect cellular stress and guide safer dietary recommendations.
- What could go wrong
- This is a small, short-term study in healthy people, so findings may not apply to the general population or to long-term use. The measured stress markers may not translate to meaningful health outcomes.
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The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Erciyes University
Kayseri, Turkey (Türkiye)