New hope for hard-to-treat gut cancers: targeted combo tested

NCT ID NCT05039177

First seen Mar 28, 2026 · Last updated May 02, 2026 · Updated 4 times

Summary

This study tested a new drug called ERAS-007 combined with other cancer treatments in 101 people with advanced colorectal or pancreatic cancer that had spread. The main goals were to find the safest dose and check for side effects. The approach targets a specific cell pathway (MAPK) to try to control tumor growth.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • City of Hope

    Duarte, California, 91010, United States

  • Duke Cancer Institute

    Durham, North Carolina, 27710, United States

  • Henry Ford Cancer Institute

    Detroit, Michigan, 48202, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02215, United States

  • Sarah Cannon Research Institute (Tennessee Oncology)

    Nashville, Tennessee, 37203, United States

  • Stephenson Cancer Center

    Oklahoma City, Oklahoma, 73104, United States

  • The Johns Hopkins Hospital

    Baltimore, Maryland, 21287, United States

  • The University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • UCSF Mount Zion Medical Ctr

    San Francisco, California, 94158, United States

  • University of Alabama at Birmingham (O'Neal Comprehensive Cancer Center)

    Birmingham, Alabama, 35233, United States

  • University of California Irvine College of Medicine

    Orange, California, 92868, United States

  • University of Washington - Seattle Cancer Care Alliance

    Seattle, Washington, 98109, United States

  • Virginia Cancer Specialists

    Fairfax, Virginia, 22031, United States

  • Washington University (Siteman Cancer Center)

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.