Lung transplant Patients' breathing reflex under scrutiny
NCT ID NCT07280611
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether a natural breathing reflex, called the Hering-Breuer reflex, still works in people who have received a double lung transplant. Researchers will place a thin tube through the nose to measure diaphragm activity while patients are on a ventilator. They will compare 11 transplant patients with 11 other ICU patients who had non-chest surgery to see if the reflex is weakened and how it changes with different ventilator pressure settings.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors better understand how lung transplants affect breathing control, potentially improving ventilator settings for these patients.
- What could go wrong
- This is a very small, early observational study with only 22 participants. It does not test a treatment, so it cannot directly lead to new therapies.
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Contacts and locations
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Locations
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Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
RECRUITINGMilan, Michigan, 20122, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••