Can a moringa, ginger, and curcuma blend quiet pregnancy nausea?
NCT ID NCT07833371
First seen Sep 22, 2026 · Last updated Sep 22, 2026
Summary
Researchers are examining whether adding a fixed-dose combination of moringa, ginger, and curcuma extracts to ondansetron helps ease nausea and vomiting in the first trimester of pregnancy. The study reviews medical records of 65 pregnant patients aged 20 to 40 who took ondansetron with or without the herbal blend as part of routine care. The main measure is the change in a standard nausea and vomiting score from the start of treatment to day three.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- a fixed-dose combination of moringa, ginger, and curcuma extracts added to ondansetron
- What this could lead to
- If the herbal combination helps, it could offer pregnant women an added option for managing nausea and vomiting in early pregnancy.
- What could go wrong
- This is a small retrospective study of existing medical records, so it can show an association but not prove cause and effect. Herbal products can vary in quality and may interact with other treatments.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 65 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2026
- Expected to finish
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Oct 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Medical records of pregnant patients aged 20-40 years with a documented gestational age of 1-12 weeks and nausea and vomiting of pregnancy who received routine clinical treatment with oral ondansetron, either alone or combined with Moringa oleifera, Zingiber officinale, and Curcuma xanthorrhiza extracts. Eligible records must contain complete baseline and day-3 PUQE scores.
- Ages
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20 to 40 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Pregnant patients aged 20 to 40 years. * Gestational age of 1 to 12 weeks documented in the medical record. * Nausea and vomiting of pregnancy. * Received oral ondansetron 4 mg twice daily for 3 days, either alone or with adjunctive Moringa oleifera, Zingiber officinale, and Curcuma xanthorrhiza extracts, as part of routine clinical care. * Complete PUQE scores available at baseline and day 3. Exclusion Criteria: * Gestational age greater than 12 weeks or gestational age not clearly documented. * Not pregnant at the time of treatment. * Nausea or vomiting documented as being attributable to a cause other than pregnancy. * Duplicate medical records. * Missing or incomplete baseline or day-3 PUQE data. * Treatment exposure that cannot be clearly classified into either study group.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Klinik Utama Permata Hati
Bandung, West Java, 40226, Indonesia
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