New hope for Tough-to-Treat colorectal cancer: experimental drug enters final testing phase

This study is testing whether a new drug called JSKN003 works better than standard treatments for people with advanced HER2-positive colorectal cancer that has stopped responding to common chemotherapy drugs. The trial will involve 123 adults whose cancer has spread and who have already tried oxaliplatin, 5-FU, and irinotecan without success. Researchers will compare how long patients live without their cancer getting worse and monitor side effects to see if JSKN003 is both effective and safe.