New combo therapy tested for Tough-to-Treat HER2 cancers
NCT ID NCT05027139
Summary
This study tested whether combining two investigational drugs, zanidatamab and evorpacept, was safe and could help treat people with advanced HER2-expressing cancers that had worsened after standard treatments. The first part of the study focused on finding safe dose levels, and the second part looked at how well the combination worked to shrink tumors. It involved 52 adults with specific types of advanced breast or stomach cancers.
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Contacts and locations
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Locations
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Astera Cancer Care
East Brunswick, New Jersey, 08816, United States
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Florida Cancer Specialists
Sarasota, Florida, 34232, United States
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Magee-Womens Hospital of UPMC
Pittsburgh, Pennsylvania, 15213, United States
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Northwest Medical Specialties, PLLC
Tacoma, Washington, 98405, United States
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The University of Texas MD Anderson Cancer Center
Houston, Texas, 77030, United States
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UC Irvine Health - Chao Family Comprehensive Cancer Center
Orange, California, 92868, United States
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UC San Diego - Moores Cancer Center
La Jolla, California, 92093, United States
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UCLA Department of Medicine Hematology/Oncology
Los Angeles, California, 90095, United States
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University Hospitals Cleveland Medical Center
Cleveland, Ohio, 44106, United States
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University of Vermont Medical Center
Burlington, Vermont, 05401, United States
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University of Wisconsin - Madison
Madison, Wisconsin, 53792, United States
Conditions
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