Scientists hunt for clues to stop hepatitis drug without relapse

NCT ID NCT06603311

First seen Mar 06, 2026 · Last updated May 16, 2026 · Updated 11 times

Summary

This study aims to find biological markers that can tell doctors when it is safe for patients with chronic hepatitis delta to stop taking the drug bulevirtide without the virus coming back. Twenty adults with stable liver disease who have been on bulevirtide for at least 48 weeks will stop treatment and be monitored for 48 weeks. Researchers will track which patients experience a return of the virus and look for patterns in their blood to predict this outcome.

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Contacts and locations

Locations

  • Charité - University Hospital Berlin (Campus Virchow-Clinic); Department of Hepatology and Gastroenterology

    Berlin, State of Berlin, 13353, Germany

  • Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico; Division of Gastroenterology and Hepatology

    Milan, 20122, Italy

  • Hannover Medical School; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology

    Hanover, Lower Saxony, 30625, Germany

  • University Hospital Frankfurt; Medical Clinic 1

    Frankfurt am Main, Hesse, 60590, Germany

  • University Hospital Heidelberg; Department of Internal Medicine IV: Gastroenterology, Hepatology, Infectious Diseases, Poisoning

    Heidelberg, Baden-Wurttemberg, 69120, Germany

Conditions

Explore the condition pages connected to this study.