New drug duo aims to knock out hepatitis d virus

NCT ID NCT06903338

Summary

This Phase 3 trial is testing whether a combination of two drugs, tobevibart and elebsiran, can effectively treat chronic hepatitis D infection. It will compare people who receive the treatment right away to those whose treatment is delayed. The main goal is to see if the treatment can reduce the hepatitis D virus to undetectable levels and improve liver health after 48 weeks.

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Contacts and locations

Locations

  • Investigative Site

    Chandler, Arizona, 85224, United States

  • Investigative Site

    Los Angeles, California, 90033, United States

  • Investigative Site

    Redwood City, California, 94063, United States

  • Investigative Site

    San Francisco, California, 94143, United States

  • Investigative Site

    DeLand, Florida, 32720, United States

  • Investigative Site

    Chicago, Illinois, 60612, United States

  • Investigative Site

    Baltimore, Maryland, 21287, United States

  • Investigative Site

    Hillsborough, New Jersey, 08844, United States

  • Investigative Site

    New York, New York, 10016, United States

  • Investigative Site

    New York, New York, 10021, United States

  • Investigative Site

    New York, New York, 10029, United States

  • Investigative Site

    Murray, Utah, 84107, United States

  • Investigative Site

    Seattle, Washington, 98105, United States

  • Investigative Site

    Calgary, Alberta, T2N 4Z6, Canada

  • Investigative Site

    Montreal, Quebec, H2L 4E9, Canada

  • Investigative Site

    Montreal, H2X 1R9, Canada

  • Investigative Site

    Ottawa, K1H8L6, Canada

  • Investigative Site

    Québec, G1V 4G2, Canada

  • Investigative Site

    Vancouver, V6Z 2C7, Canada

  • Investigative Site

    Tbilisi, 0102, Georgia

  • Investigative Site

    Tbilisi, 0114, Georgia

  • Investigative Site

    Tbilisi, 0159, Georgia

  • Investigative Site

    Frankfurt, 60590, Germany

  • Investigative Site

    Hanover, 30625, Germany

  • Investigative Site

    Heidelberg, 69120, Germany

  • Investigative Site

    Chisinau, 2025, Moldova

  • Investigative Site

    Auckland, 1010, New Zealand

  • Investigative Site

    Karachi, 74800, Pakistan

  • Investigative Site

    Karachi, 75600, Pakistan

  • Investigative Site

    Lahore, 54800, Pakistan

  • Investigative Site

    Rawalpindi, 46000, Pakistan

  • Investigative Site

    Bucharest, 021105, Romania

  • Investigative Site

    Bucharest, 022328, Romania

  • Investigative Site

    Bucharest, 030303, Romania

  • Investigative Site

    Kyiv, 01135, Ukraine

  • Investigative Site

    London, E1 1BB, United Kingdom

  • Investigative Site

    London, SE5 9RS, United Kingdom

  • Investigative Site

    Manchester, M8 5RB, United Kingdom

  • Investigative Site

    Nottingham, NG7 2UH, United Kingdom

Conditions

Explore the condition pages connected to this study.