Scientists hunt for clues to stop lifelong hepatitis d drugs

NCT ID NCT06603311

Summary

This study aims to find biological markers in the blood or liver that can tell doctors when it might be safe for patients with chronic hepatitis D to stop taking the drug bulevirtide. Researchers will stop treatment in 20 patients whose virus is well-controlled and monitor them for a year to see who stays healthy and who relapses. The goal is to personalize treatment, potentially reducing long-term medication use and the risk of dangerous viral flare-ups.

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Contacts and locations

Locations

  • Charité - University Hospital Berlin (Campus Virchow-Clinic); Department of Hepatology and Gastroenterology

    Berlin, State of Berlin, 13353, Germany

  • Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico; Division of Gastroenterology and Hepatology

    Milan, 20122, Italy

  • Hannover Medical School; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology

    Hanover, Lower Saxony, 30625, Germany

  • University Hospital Frankfurt; Medical Clinic 1

    Frankfurt am Main, Hesse, 60590, Germany

  • University Hospital Heidelberg; Department of Internal Medicine IV: Gastroenterology, Hepatology, Infectious Diseases, Poisoning

    Heidelberg, Baden-Wurttemberg, 69120, Germany

Conditions

Explore the condition pages connected to this study.