HIV patients get new hope against hepatitis b with tailored vaccine strategy

NCT ID NCT00480792

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested three different ways of giving the hepatitis B vaccine to 437 people with HIV whose CD4 counts were above 200. The goal was to see which schedule—standard dose, double dose, or skin injections—works best to protect them from hepatitis B, a virus that can cause serious liver damage in HIV patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

GenHevac B Pasteur (hepatitis B vaccine)

What this could lead to

If successful, this could identify a more effective hepatitis B vaccination schedule for people with HIV, reducing their risk of severe liver disease.

What could go wrong

This trial is completed, so results are available. However, the vaccine may still be less effective in some HIV patients, and protection may not last long-term.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease hepatitis B virus infection prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hopital Cochin CIC de vaccinologie

    Paris, 75014, France