Breakthrough drug trial aims to cure chronic hepatitis b

NCT ID NCT05630820

ACTIVE_NOT_RECRUITING ⭐️ CURE ⭐️ Sponsor: GlaxoSmithKline Source: ClinicalTrials.gov ↗

Summary

This large, late-stage study is testing whether a drug called bepirovirsen can provide a 'functional cure' for people with chronic Hepatitis B. It involves 857 participants who are already on standard medication. The main goal is to see if the treatment can suppress the virus to undetectable levels and allow patients to safely stop all medications long-term.

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Centreville, Alabama, 35042, United States
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Los Angeles, California, 90033, United States
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San Francisco, California, 94115, United States
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San Francisco, California, 94121, United States
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Colorado Springs, Colorado, 80907, United States
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Ft. Pierce, Florida, 34982, United States
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Miami, Florida, 33136, United States
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Glen Burnie, Maryland, 21061, United States
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Minneapolis, Minnesota, 55404, United States
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Philadelphia, Pennsylvania, 19104, United States
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Denison, Texas, 75020, United States
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Seattle, Washington, 98104, United States
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Buenos Aires, 1023, Argentina
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Buenos Aires, C1425AGC, Argentina
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Ciudad Autonoma de Bueno, C1056ABI, Argentina
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Santa Fe, 3000, Argentina
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Westmead, New South Wales, 2145, Australia
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Herston, Queensland, 4029, Australia
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Box Hill, Victoria, 3128, Australia
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Fitzroy, Victoria, 3065, Australia
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Botucatu, 18618-686, Brazil
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Fortaleza, 60430-372, Brazil
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Nova Iguaçu, 26030-380, Brazil
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Porto Alegre, 90020-090, Brazil
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Porto Alegre, 90035003, Brazil
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Rio de Janeiro, 21045-900, Brazil
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Salvador, 40110160, Brazil
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Vitória, 29043260, Brazil
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Plovdiv, 4002, Bulgaria
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Sliven, 8800, Bulgaria
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Sofia, 1797, Bulgaria
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Varna, 9020, Bulgaria
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Calgary, Alberta, T2N 4N1, Canada
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Edmonton, Alberta, T6G 2B7, Canada
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Edmonton, Alberta, T6G 2X8, Canada
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Halifax, Nova Scotia, B3H 2Y9, Canada
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Toronto, Ontario, M6H 3M1, Canada
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Montreal, Quebec, H2L 4E9, Canada
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Montreal, Quebec, H2L 4P9, Canada
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Regina, Saskatchewan, S4P 0W5, Canada
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Beijing, 100015, China
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Beijing, 100032, China
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Changchun, 130021, China
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Chengdu, 610072, China
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Chongqing, 400042, China
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Guangzhou, 510515, China
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Guangzhou, 510630, China
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Hangzhou, 310000, China
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Hangzhou, 310003, China
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Hefei, 230022, China
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Kunming, 650021, China
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Liuchow, China
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Nanjing, 210003, China
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Shanghai, 200025, China
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Shanghai, 200052, China
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Shenzhen, 518023, China
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Taiyuan, 030001, China
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Tianjin, 300000, China
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Ürümqi, 830054, China
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Wuhan, 430022, China
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Xi'an, 710061, China
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Xiamen, 361015, China
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Zhengzhou, 450000, China
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Zunyi, 563114, China
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Créteil, 94010, France
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Grenoble, 38043, France
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Limoges, 87042, France
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Lyon, 69317, France
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Paris, 75651, France
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Rouen, 76031, France
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Toulouse, 31059, France
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Frankfurt, 60329, Germany
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Frankfurt, 60596, Germany
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Hamburg, 20146, Germany
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Hanover, 30625, Germany
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Athens, 115 27, Greece
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Heraklion Crete, 715 00, Greece
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Thessaloniki, 54642, Greece
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Szeged, 6725, Hungary
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Székesfehérvár, 8000, Hungary
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Zalaegerszeg, Hungary
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Ahmedabad, 380009, India
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Chennai, 600035, India
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Kanpur, 208002, India
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Kochi, 682026, India
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Kolkata, 700150, India
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Kolkata, India
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Mumbai, 400012, India
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Mumbai, 400022, India
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Nagpur, 441108, India
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New Delhi, 110029, India
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New Delhi, 110060, India
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New Delhi, 110070, India
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Pune, 411001, India
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Raipur, India
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Secunderabad, 500003, India
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Milan, 20157, Italy
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Napoli, 80131, Italy
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Padua, 35128, Italy
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Palermo, 90127, Italy
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Pisa, 56124, Italy
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Roma, 00133, Italy
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Sassari, 07100, Italy
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Torino, 10126, Italy
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Fukui, 918-8503, Japan
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Hiroshima, 730-8619, Japan
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Hokkaido, 006-8555, Japan
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Hokkaido, 060-8648, Japan
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Hokkaido, 062-8618, Japan
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Ishikawa, 920-8650, Japan
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Kagawa, 760-8557, Japan
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Kumamoto, 860-8556, Japan
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Nagasaki, 856-8562, Japan
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Nara, 634-8522, Japan
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Niigata, 950-1104, Japan
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Osaka, 565-0871, Japan
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Tokyo, 113-8603, Japan
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Yamaguchi, 750-0061, Japan
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Yamanashi, 409-3898, Japan
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Johor Bahru, 80100, Malaysia
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Kota Bharu Kelantan, Malaysia
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Kota Kinabalu, Malaysia
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Kuala Lumpur, 59100, Malaysia
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Kuala Terengganu, 20400, Malaysia
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Kuantan, 25100, Malaysia
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Aguascalientes, 20010, Mexico
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Auckland, 1023, New Zealand
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Papatoetoe Auckland, 2025, New Zealand
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Panama City, Panama
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Cebu City, 6000, Philippines
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Makati City, 1229, Philippines
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Pasig, 1605, Philippines
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Silang, 4118, Philippines
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Gdansk, 80-405, Poland
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Mysłowice, 41-400, Poland
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Żychlin, 62-571, Poland
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Bucharest, 020475, Romania
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Bucharest, 030303, Romania
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Cluj-Napoca, 400348, Romania
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Constanța, 900709, Romania
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Galati, 800179, Romania
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Oradea, 410469, Romania
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Ansan, 15355, South Korea
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Incheon, 405-760, South Korea
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Pusan, 49241, South Korea
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Seoul, 03312, South Korea
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Seoul, 05505, South Korea
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Ulsan, 44033, South Korea
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Alcorcon Madrid, Spain
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Badajoz, 06080, Spain
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Granada, 18016, Spain
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Madrid, 28006, Spain
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Madrid, 28032, Spain
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Madrid, 28046, Spain
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Sabadell Barcelona, 08208, Spain
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Seville, 41013, Spain
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Valencia, 46026, Spain
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Valladolid, 47012, Spain
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Zaragoza, 50009, Spain
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Kaohsiung City, 824, Taiwan
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Taichung, 404, Taiwan
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Tainan, 704, Taiwan
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Taipei, 100, Taiwan
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Chiang Mai, 50200, Thailand
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Ankara, 06590, Turkey (Türkiye)
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Istanbul, 34010, Turkey (Türkiye)
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Izmir, 35100, Turkey (Türkiye)
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Liverpool, L7 8XP, United Kingdom
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London, WC1E 6JB, United Kingdom
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Middlesbrough, TS4 3BW, United Kingdom
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Newcastle upon Tyne, NE7 7DN, United Kingdom