Scientists test drug cocktails in quest for functional cure for hepatitis b
NCT ID NCT04225715
Summary
This study tested several new combination drug therapies to see if they could help control and potentially clear chronic Hepatitis B infection. It involved 281 adults with stable liver function who were already on standard antiviral medication. The main goal was to see if the new combinations were safe and could lead to the loss of a key viral marker (HBsAg) after stopping treatment, which is a step towards better long-term control of the disease.
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Contacts and locations
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Locations
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Asan Medical Center / Clinical Trial Center
Seoul, 138-736, South Korea
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Auckland Clinical Studies Limited
Auckland, 1010, New Zealand
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Beijing Friendship Hospital
Beijing, 100050, China
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Changhua Christian Hospital
Chang-hua, 500, Taiwan
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China Medical University Hospital
Taichung, 40447, Taiwan
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Chuncheon Sacred Heart Hospital
Gangwon-Do, 200-704, South Korea
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HIVNAT
Bangkok, 10330, Thailand
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Hopital Beaujon
Clichy, 92118, France
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Hospital Alvaro Cunqueiro
Vigo, Pontevedra, 36212, Spain
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Hospital San Juan de Dios La Serena
La Serena, 1700000, Chile
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Huashan Hospital, Fudan University
Shanghai, 200040, China
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Kaohsiung Medical University Chung-Ho Memorial Hospital
Kaohsiung City, 807, Taiwan
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King College Hospital NHS Foundation Trust
London, SE5 9RS, United Kingdom
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Maharaj Nakorn Chiang Mai Hospital
Chiang Mai, 50200, Thailand
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Middlemore Clinical Trials
Auckland, New Zealand
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Nanfang Hospital, Southern Medical University
Guangzhou, 510515, China
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National Cheng Kung Univ Hosp
Tainan, 00704, Taiwan
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National Taiwan University Hospital
Taipei, 10002, Taiwan
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Queen Mary Hospital
Hong Kong, Hong Kong
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Ruijin Hospital Shanghai Jiaotong University School of Medicine
Shanghai, 200025, China
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SMG-SNU Boramae Medical Center
Seoul, 156-707, South Korea
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Seoul National University College of Medicine, Liver Research Institute
Seoul, South Korea
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Siriraj Hospital
Bangkok, 10700, Thailand
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Spitalul Clinic Judetean de Urgenta Cluj Napoca
Cluj-Napoca, 400006, Romania
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Taichung Veterans General Hospital
Taichung, 40705, Taiwan
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The First Hospital of Jilin University
Changchun, 130021, China
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Tokuda Hospital Sofia
Sofia, 1407, Bulgaria
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Toronto Liver Centre
Toronto, Ontario, M6H 3M1, Canada
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Uni of Alberta Hospital
Edmonton, Alberta, T6G 2S2, Canada
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University Multiprofile Hospital For Active Treatment "Sveti Ivan Rilski" EAD
Sofia, 1431, Bulgaria
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University of Calgary
Calgary, Alberta, T2N 2T9, Canada
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Vall d?Hebron Institute of Oncology (VHIO), Barcelona
Barcelona, 08035, Spain
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West China Hospital, Sichuan University
Chengdu, 610041, China
Conditions
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