One-Time gene injection aims to free hemophilia patients from constant treatments

NCT ID NCT03307980

Summary

This study is following people with Hemophilia B who received an experimental gene therapy to see how safe and effective it remains over the long term. It also includes a new group testing a higher dose of the same therapy. The goal is to see if a single treatment can help the body produce its own clotting factor, reducing or eliminating the need for regular infusions and bleeding episodes.

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Contacts and locations

Locations

  • Ege Universitesi Tip Fakultesi Cocuk Sagligi ve Hastaliklari Anabilim Dali

    Izmir, 35100, Turkey (Türkiye)

  • Istanbul Universitesi Onkoloji Enstitusu Çocuk Hematoloji Onkoloji Bilim Dali

    Istanbul, 34093, Turkey (Türkiye)

  • Istanbul University Clinical Trials Excellence Center

    Istanbul, 34452, Turkey (Türkiye)

  • LA Center for Bleeding and Clotting Disorders

    New Orleans, Louisiana, 70112, United States

  • LA Center for Bleeding and Clotting Disorders - Metairie

    Metairie, Louisiana, 70001, United States

  • Louisiana Center for Advanced Medicine

    Slidell, Louisiana, 70461, United States

  • McGill University Health Center - Research Institute

    Montreal, Quebec, H4A 3J1, Canada

  • McMaster University

    Hamilton, Ontario, L8S 3L8, Canada

  • McMaster University Medical Centre - Hamilton Health Sciences

    Hamilton, Ontario, L8N 3Z5, Canada

  • Mississippi Center for Advanced Medicine

    Madison, Mississippi, 39110, United States

  • Royal Prince Alfred Hospital

    Camperdown, New South Wales, 2050, Australia

  • The Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

  • The Research Institute of the McGill University Health Centre

    Montreal, Quebec, H3H 2R9, Canada

  • Tulane Lakeside Hospital

    Metairie, Louisiana, 70001, United States

  • Tulane University Clinical Translational Unit

    New Orleans, Louisiana, 70112, United States

  • Tulane University Hospitals and Clinic

    New Orleans, Louisiana, 70112, United States

  • Tulane University School of Medicine

    New Orleans, Louisiana, 70112, United States

  • UC Davis Comprehensive Cancer Center

    Sacramento, California, 95817, United States

  • UC Davis Ellison Ambulatory Care Clinic

    Sacramento, California, 95817, United States

  • UC Davis Medical Center

    Sacramento, California, 95817, United States

  • UC Davis Medical Center department of Radiology

    Sacramento, California, 95817, United States

  • UC Davis Midtown Cancer Center

    Sacramento, California, 95817, United States

  • UC DavisHealth Main Hospital

    Sacramento, California, 95817, United States

  • University Medical Center New Orleans

    New Orleans, Louisiana, 70112, United States

  • Weill Cornell Medicine - New York Presbyterian Hospital

    New York, New York, 10065, United States

Conditions

Explore the condition pages connected to this study.