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Could a Height-Based anesthesia dose prevent dangerous drops in blood pressure?

NCT ID NCT07751835

Disease control Sponsor: Liaquat National Hospital & Medical College Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 07, 2026 · Last updated Aug 07, 2026

Summary

This trial tests whether giving spinal anesthesia based on a person's height, rather than a standard fixed dose, can reduce side effects like low blood pressure and slow heart rate during lower limb surgeries. Adults aged 18 to 65 with mild health conditions are eligible to participate. The study compares the two dosing methods to see which one leads to fewer complications.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Height-based dose of hyperbaric bupivacaine 0.5% (spinal anesthetic)
What this could lead to
If height-based dosing works, it could make spinal anesthesia safer and more comfortable for patients undergoing lower limb surgeries by reducing side effects like low blood pressure and slow heart rate.
What could go wrong
This is an early-phase trial with a small number of participants, so results may not apply to everyone. The height-based dose might not consistently reduce side effects, and there is always a risk of allergic reactions or other anesthesia-related complications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 1/2

Runs two stages together: safety and dose first, then whether the treatment works.

Participants

About 104 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * both genders. 18-65 years age ASA physical status I and II Exclusion Criteria: * ASA III and IV Refusal of patient Height less than 150 cm Known allergy to study drug

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lower limb surgeries

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.