Plugging the leak: new device aims to fix dangerous heart valve gaps

NCT ID NCT04489823

Summary

This study is testing a small plug device to seal leaks that can form around surgically replaced heart valves. The leaks can cause heart failure or severe anemia. Researchers will implant the plug in 200 adults with significant leaks to see if it safely and effectively closes the gap and improves their health.

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Contacts and locations

Locations

  • Baptist Memorial Hospital

    Memphis, Tennessee, 38120, United States

  • Carilion Roanoke Memorial Hospital

    Roanoke, Virginia, 24014, United States

  • Edinburgh Heart Centre

    Edinburgh, Lothian, EH16 4SA, United Kingdom

  • Emory University Hospital

    Atlanta, Georgia, 30322, United States

  • Gornoslaskie Centrum Medyczne im.prof. Leszka Gieca

    Katowice, Silesian Voivodeship, 40-635, Poland

  • Hackensack University Medical Center

    Hackensack, New Jersey, 07601, United States

  • Hospital Ramón y Cajal

    Madrid, Madrid, 28034, Spain

  • Hospital Universitario de Salamanca

    Salamanca, Spain

  • Institut de Cardiologie de Montreal (Montreal Heart Inst.)

    Montreal, Quebec, H1T 1C8, Canada

  • Institut de Cardiologie de Quebec (Hôpital Laval)

    Québec, Quebec, G1V 4G5, Canada

  • Intermountain Medical Center

    Murray, Utah, 84157, United States

  • Lenox Hill Hospital

    New York, New York, 10021, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Minneapolis Heart Institute

    Minneapolis, Minnesota, 55407, United States

  • New York Presbyterian Hospital/Cornell University

    New York, New York, 10021, United States

  • Ospedale San Raffaele

    Milan, Lombard, 20132, Italy

  • Papworth Hospital NHS Foundation Trust

    Cambridge, United Kingdom

  • Providence Sacred Heart Medical Center

    Spokane, Washington, 99202, United States

  • Saint Luke's Hospital of Kansas City

    Kansas City, Missouri, 64111, United States

  • St. Antonius Ziekenhuis

    Nieuwegein, Utrecht, 3435 CM, Netherlands

  • The Cleveland Clinic Foundation

    Cleveland, Ohio, 44195, United States

  • The Royal Sussex County Hospital

    Brighton, Soeast, BN25BE, United Kingdom

  • University Hospital - Univ. of Alabama at Birmingham (UAB)

    Birmingham, Alabama, 35249, United States

  • University of Nebraska Medical Center

    Omaha, Nebraska, 68198, United States

Conditions

Explore the condition pages connected to this study.