Year-Long heart drug safety check for 300 teens

NCT ID NCT03013751

Summary

This study followed 301 adolescents with single ventricle heart disease for one year to check the long-term safety of a medication called udenafil. All participants received the drug while researchers monitored for side effects and measured changes in exercise capacity, heart function, and quality of life. The goal was to gather safety information to support the potential use of this medication for managing this complex heart condition.

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Contacts and locations

Locations

  • Boston Children's Hospital

    Boston, Massachusetts, 02115, United States

  • Cedars/Sinai Heart Institute

    Los Angeles, California, 90048, United States

  • Children's Healthcare of Atlanta

    Atlanta, Georgia, 30322, United States

  • Children's Hospital Colorado

    Aurora, Colorado, 80045, United States

  • Children's Hospital of New York

    New York, New York, 10032, United States

  • Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

  • Children's Hospital of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

  • Children's Mercy Hospital Kansas City

    Kansas City, Missouri, 64108, United States

  • Children's National Medical Center

    Washington D.C., District of Columbia, 20008, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Johns Hopkins All Children's Heart Institute

    St. Petersburg, Florida, 33701, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • Nemours Cardiac Center/Alfred I. duPont Hospital for Children

    Wilmington, Delaware, 19803, United States

  • Phoenix Children's Hospital/Children's Heart Center at Phoenix Children's Hospital

    Phoenix, Arizona, 85016, United States

  • Primary Children's Medical Hospital/Dept. of Pediatric Cardiology

    Salt Lake City, Utah, 84113, United States

  • Rady Children's Hospital

    San Diego, California, 92123, United States

  • Riley Hospital for Children/Herman B. Wells Center for Pediatric Research

    Indianapolis, Indiana, 46201, United States

  • Seattle Children's Hosptial

    Seattle, Washington, 98105, United States

  • Sejong General Hospital

    Bucheon-si, Gyeonggi-do, 14754, South Korea

  • Seoul National University Children's Hospital

    Seoul, 110-744, South Korea

  • Texas Children's Hospital

    Houston, Texas, 77030, United States

  • The Hospital for Sick Children

    Toronto, Ontario, ON M5G 1X8, Canada

  • University of Michigan Congenital Heart Center/C.S. Mott Children's Hospital

    Ann Arbor, Michigan, 48109-4204, United States

  • Washington University St. Louis/St.Louis Children's Hospital

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.