Novartis tests inflammation fighters for High-Risk hearts
NCT ID NCT06097663
Summary
This study tested if two experimental drugs, DFV890 (a daily pill) and MAS825 (a single injection), could safely reduce specific markers of inflammation in the blood of people with coronary heart disease and a genetic blood condition (CHIP). About 31 adults who had a prior heart attack and specific CHIP mutations took part in this 12-week, placebo-controlled trial. The main goal was to see how well the drugs lowered inflammation markers like IL-6 and IL-18, which are linked to heart disease risk.
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Contacts and locations
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Locations
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Novartis Investigative Site
Montreal, Quebec, H1T 1C8, Canada
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Novartis Investigative Site
Frankfurt am Main, Hesse, 60590, Germany
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Novartis Investigative Site
Bonn, 53105, Germany
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Novartis Investigative Site
München, 80636, Germany
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Vanderbilt University Medical Cent
Nashville, Tennessee, 37232-8805, United States
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Washington University
St Louis, Missouri, 63110, United States
Conditions
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