Race against time: new shot aims to save heart attack patients before hospital

NCT ID NCT04825743

Summary

This large, late-stage study is testing if a single injection given by paramedics in the ambulance can improve survival and recovery for people having a major heart attack (STEMI). Over 2,400 patients will receive either the experimental drug zalunfiban or a placebo shot, with researchers tracking outcomes like death, stroke, and heart failure over the next year. The goal is to start treatment faster to limit heart damage before the patient reaches the hospital for standard procedures.

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Contacts and locations

Locations

  • Amphia Ziekenhuis

    Breda, Netherlands

  • Amsterdam UMC

    Amsterdam, Netherlands

  • Amsterdam UMC, locatie AMC

    Amsterdam, Netherlands

  • André Grégoire Hospital - GHT GPNE

    Montreuil, France

  • Bacs-Kiskun County Teaching Hospital

    Kecskemét, Hungary

  • Baylor College of Medicine

    Houston, Texas, 77030, United States

  • Bichat-Claude Bernard Hospital

    Paris, France

  • Corewell Health William Beaumont University Hospital

    Royal Oak, Michigan, 48073, United States

  • ETZ TweeSteden

    Tilburg, Netherlands

  • Emergency Clinical County Hospital Targu-Mures

    Târgu Mureş, Romania

  • Emergency Clinical Hospital "Bagdasar-Arseni", Bucharest

    Bucharest, Romania

  • Emergency University Hospital Bucharest

    Bucharest, Romania

  • European Hosital de Paris - GVM Care & Research (La Roseraie)

    Aubervilliers, France

  • Grenoble Alpes University Hospital

    Grenoble, France

  • Henri Mondor University Hospital

    Créteil, France

  • Hospital Ambroise Pare

    Boulogne-Billancourt, 92100, France

  • Hôpital Cochin

    Paris, France

  • Institute for Cardiovascular Diseases Timisoara

    Timișoara, Romania

  • Institute of Cardiovascular Diseases "Prof. George I.M. Georgescu" Iasi

    Iași, Romania

  • Instituto Nacional de Cardiologia "Ignacio Chavez"

    Mexico City, D.F., 14080, Mexico

  • Isala

    Zwolle, Netherlands

  • Jeroen Bosch Ziekenhuis

    's-Hertogenbosch, Netherlands

  • Lariboisière Hospital AP-HP

    Paris, France

  • Leiden University Medical Center

    Leiden, Netherlands

  • Maastricht UMC

    Maastricht, Netherlands

  • Medisch Spectrum Twente

    Enschede, Netherlands

  • Providence Alaska Medical Center

    Anchorage, Alaska, 99508, United States

  • Regional University Hospital of Rennes - Hospital Ponchaillou

    Rennes, France

  • Rijnstate Arnhem

    Arnhem, Netherlands

  • Semmelweis University Heart and Vascular Center

    Budapest, Hungary

  • Slingeland Ziekenhuis

    Doetinchem, Netherlands

  • St. Anne's University hospital

    Brno, Czechia

  • St. Antonius Ziekenhuis

    Nieuwegein, 3435 CM, Netherlands

  • Tergooi Blaricum

    Blaricum, Netherlands

  • UMC Utrecht

    Utrecht, Netherlands

  • UT Southwestern Medical Center

    Dallas, Texas, 75390, United States

  • University Hospital Brno

    Brno, Czechia

  • University Hospital De La Pitié-Salpêtrière

    Paris, France

  • University Hospital of Marseille - La Timone Hospital

    Marseille, France

  • University of Alberta

    Edmonton, Canada

  • University of Debrecen

    Debrecen, H4032, Hungary

  • Viecuri Medisch Centrum

    Venlo, Netherlands

  • Washington University

    St Louis, Missouri, 63110, United States

  • Ziekenhuis Gelderse Vallei

    Ede, Netherlands

  • Zuyderland MC

    Heerlen, Limberg, Netherlands

Conditions

Explore the condition pages connected to this study.