Breakthrough injection tested to save lives after severe heart attacks

NCT ID NCT04837001

Summary

This large, completed Phase 3 trial tested whether an intravenous drug called FDY-5301 could help patients survive and avoid heart failure after a major, life-threatening heart attack (anterior STEMI). Over 2,300 patients who received emergency artery-opening surgery (PCI) were randomly given either the study drug or a placebo. The main goal was to see if the drug reduced deaths from heart problems or new heart failure events.

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Contacts and locations

Locations

  • 4. Military Clinical Hospital with Polyclinic SP ZOZ

    Wroclaw, 50-981, Poland

  • Allina Health System

    Minneapolis, Minnesota, 55407, United States

  • Bajcsy-Zsilinszky Kórház és Rendelőintézet IV. Belgyógyászat és Kardiológia, Intenzív Coronaria Egység, Haemodinamikai Osztály

    Budapest, 1106, Hungary

  • Borsod-Abaúj-Zemplén Megyei Központi Kórház és Egyetemi Oktatókórház

    Miskolc, 3526, Hungary

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Budai Irgalmasrendi Kórház

    Budapest, 1023, Hungary

  • Bács-Kiskun Vármegyei Oktatókórház

    Kecskemét, 6000, Hungary

  • Center for Invasive Cardiology

    Krosno, 38-400, Poland

  • Central Clinical Hospital of the Medical University of Łódź

    Lodz, 92-213, Poland

  • Centro Hospitalar Universitário Lisboa Central

    Lisbon, 1169-024, Portugal

  • Centro Hospitalar Universitário Lisboa Norte

    Lisbon, 1649-035, Portugal

  • Centro Hospitalar Universitário do Porto

    Porto, 4099-001, Portugal

  • Centro Hospitalar Vila Nova de Gaia/Espinho

    Vila Nova de Gaia, 4434-502, Portugal

  • Centro Hospitalar e Universitário de Coimbra

    Coimbra, 3000-075, Portugal

  • Fejér Vármegyei Szent György Egyetemi Oktató Kórház

    Székesfehérvár, 8000, Hungary

  • Galilee Medical Center

    Nahariya, 2210001, Israel

  • Gottsegen György Országos Kardiológiai Intézet

    Budapest, 1096, Hungary

  • Hadassah Ein Karem Medical Center

    Jerusalem, 9112001, Israel

  • Harbor-UCLA Medical Center

    Torrance, California, 90502, United States

  • Hospital Garcia da Orta

    Almada, Setúbal District, 2805-267, Portugal

  • Hospital de Braga

    Braga, 4710-243, Portugal

  • Independent Public Provincial Hospital

    Zamość, 22-400, Poland

  • Independent Public Specialist Hospital of the West st. John Paul II

    Grodzisk Mazowiecki, 05-825, Poland

  • Lehigh Valley Hospital

    Allentown, Pennsylvania, 18103, United States

  • Meir Medical Center

    Kfar Saba, 4428164, Israel

  • Provincial Specialist Hospital in Wrocław

    Wroclaw, 51-124, Poland

  • Pécsi Tudományegyetem Klinikai Kozpönt Szívgyógyászati Klinika

    Pécs, 7624, Hungary

  • Rabin Medical Center, Beilinson Hospital

    Petah Tikva, 4941492, Israel

  • Rambam Health Care Campus

    Haifa, 3109601, Israel

  • SP ZOZ Szpital Uniwersytecki w Krakowie

    Krakow, 30-688, Poland

  • Samodzielny Publiczny Szpital Kliniczny nr 4 w Lublinie

    Lublin, 20-954, Poland

  • Scanmed Centrum Kardiologii Kutno

    Kutno, 99-300, Poland

  • Semmelweis Egyetem Városmajori Szív- és Érgyógyászati Klinika

    Budapest, 1122, Hungary

  • Shaare Zedek Medical Center

    Jerusalem, 91301, Israel

  • Shamir (Assaf Harofeh) Medical Center

    Be’er Ya‘aqov, 7033001, Israel

  • Sheba Medical Center

    Ramat Gan, 5265601, Israel

  • Somogy Vármegyei Kaposi Mór Oktató Kórház, Kardiológiai Osztály

    Kaposvár, 7400, Hungary

  • Sourasky Medical Center

    Tel Aviv, 6423906, Israel

  • Southlake Regional Health Center

    Newmarket, Ontario, L3Y 2P9, Canada

  • Sparrow Clinical Research Institute

    Lansing, Michigan, 48912, United States

  • Szabolcs-Szatmár-Bereg Vármegyei Oktatókórház, Nyíregyházi Jósa András Tagkórház

    Nyíregyháza, 4400, Hungary

  • University of Florida Health

    Jacksonville, Florida, 32209, United States

  • Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego we Wrocławiu

    Wroclaw, 50-556, Poland

  • Uniwersytecki Szpital Kliniczny im. Wojskowej Akademii Medycznej

    Lodz, 90-549, Poland

  • Uniwersytecki Szpital Kliniczny w Białymstoku

    Bialystok, 15-276, Poland

  • Uniwersyteckie Centrum Kliniczne

    Gdansk, 80-214, Poland

  • Vas Vármegyei Markusovszky Egyetemi Oktatókórház

    Szombathely, 9700, Hungary

  • Wojewódzki Szpital Zespolony im. L. Rydygiera w Toruniu

    Torun, 87-100, Poland

  • Wojskowy Szpital Kliniczny z Poliklinika SPZOZ w Lublinie

    Lublin, 20-049, Poland

  • Zala Megyei Szent Rafael Kórház

    Zalaegerszeg, 8900, Hungary

  • Ziv Medical Center

    Safed, 13110, Israel

  • Észak-Pesti Centrumkórház - Honvédkórház

    Budapest, 1134, Hungary

Conditions

Explore the condition pages connected to this study.