Major trial aims to save lives from rare heart disease

NCT ID NCT07052903

Recruiting now Disease control Sponsor: Alnylam Pharmaceuticals Source: ClinicalTrials.gov ↗

Summary

This large study is testing whether a new drug called nucresiran can help people with a serious heart condition called ATTR amyloidosis cardiomyopathy. Researchers want to see if the drug reduces deaths and hospital visits compared to a placebo. The study will involve 1,250 participants worldwide who have this progressive heart disease.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

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Locations

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La Jolla, California, 92037, United States
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Stanford, California, 94305, United States
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Norwich, Connecticut, 06360, United States
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Washington D.C., District of Columbia, 20010, United States
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Brandon, Florida, 33511, United States
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Miami, Florida, 33125, United States
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Atlanta, Georgia, 30309, United States
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Gainesville, Georgia, 30501, United States
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Tucker, Georgia, 30084, United States
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Indianapolis, Indiana, 46202, United States
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Indianapolis, Indiana, 46260, United States
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Kansas City, Kansas, 66160, United States
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Baltimore, Maryland, 21287, United States
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Boston, Massachusetts, 02115, United States
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Boston, Massachusetts, 02118, United States
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Detroit, Michigan, 48202, United States
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Rochester, Minnesota, 55905, United States
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St Louis, Missouri, 63110, United States
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Manhasset, New York, 11030, United States
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New York, New York, 10029, United States
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New York, New York, 10032, United States
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New York, New York, 10065, United States
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The Bronx, New York, 10467, United States
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Charlotte, North Carolina, 28204, United States
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Cleveland, Ohio, 44195, United States
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Lancaster, Pennsylvania, 17602, United States
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Philadelphia, Pennsylvania, 19104, United States
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Dallas, Texas, 75246, United States
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Houston, Texas, 77030, United States
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Plano, Texas, 75024, United States
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Salt Lake City, Utah, 84132, United States
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Charlottesville, Virginia, 22903, United States
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Norfolk, Virginia, 23507, United States
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Spokane, Washington, 99204, United States
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Buenos Aires, C1025ABI, Argentina
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Buenos Aires, C1093AAS, Argentina
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Buenos Aires, C1199ABB, Argentina
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Buenos Aires, C1428, Argentina
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Rosario, S2000DEJ, Argentina
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Rosario, S2000DSR, Argentina
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Rosario, S2000GAP, Argentina
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Adelaide, 5000, Australia
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Bedford Park, 5042, Australia
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Box Hill, 3128, Australia
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Chermside, 4032, Australia
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Darlinghurst, 2010, Australia
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Joondalup, 6027, Australia
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Westmead, 2145, Australia
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Braunau am Inn, 5280, Austria
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Graz, 8036, Austria
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Vienna, 1090, Austria
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Vienna, 1160, Austria
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Vienna, 1210, Austria
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Wels, 4600, Austria
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Aalst, 9300, Belgium
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Bruges, 8000, Belgium
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Brussels, 1200, Belgium
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Dendermonde, 9200, Belgium
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Genk, 3600, Belgium
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Ghent, 9000, Belgium
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Hasselt, 3500, Belgium
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Leuven, 3000, Belgium
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Liège, 4000, Belgium
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Roeselare, 8800, Belgium
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Belo Horizonte, 30220-140, Brazil
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Porto Alegre, 90035-903, Brazil
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Porto Alegre, 90560-032, Brazil
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Ribeirão Preto, 14026-900, Brazil
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Ribeirão Preto, 14051-140, Brazil
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Salvador, 40170-130, Brazil
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São Paulo, 04038-002, Brazil
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São Paulo, 05403-000, Brazil
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London, N6A 5A5, Canada
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Santiago, 7500588, Chile
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Santiago, 8320000, Chile
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Dongcheng, 100006, China
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Brno, 602 00, Czechia
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Ostrava, 708-52, Czechia
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Prague, 128 21, Czechia
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Aarhus N, 8200, Denmark
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København Ø, 2100, Denmark
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Odense C, 5000, Denmark
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Chambray-lès-Tours, 37170, France
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Dijon, 21000, France
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La Tronche, 38700, France
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Marseille, 13005, France
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Martinique, 97261, France
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Montpellier, 34295, France
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Paris, 75015, France
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Paris, 75018, France
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Pessac, 33600, France
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Reims, 51100, France
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Rennes, 35000, France
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Rouen, 76031, France
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Saint-Herblain, 44093, France
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Strasbourg, 67091, France
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Toulouse, 31059, France
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Berlin, 13353, Germany
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Cologne, 50937, Germany
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Göttingen, 37075, Germany
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Hanover, 30625, Germany
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Leipzig, 04103, Germany
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Munich, 81377, Germany
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Münster, 48149, Germany
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Würzburg, 97080, Germany
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Athens, 115 27, Greece
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Athens, 115 28, Greece
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Heraklion, 714 09, Greece
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Thessaloniki, 546 36, Greece
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Hong Kong, 999077, Hong Kong
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Budapest, 1085, Hungary
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Be’er Ya‘aqov, 70300, Israel
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Haifa, 3109601, Israel
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Jerusalem, 91120, Israel
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Petah Tikva, 4941492, Israel
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Ancona, 60126, Italy
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Bologna, 40138, Italy
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Brescia, 25123, Italy
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Florence, 50134, Italy
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Forlì, 47121, Italy
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Milan, 20122, Italy
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Naples, 80131, Italy
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Padova, 35128, Italy
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Pavia, 27100, Italy
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Pisa, 56124, Italy
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Rimini, 47923, Italy
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Roma, 00168, Italy
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Rome, 00161, Italy
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Torino, 10126, Italy
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Bunkyō City, 113-8655, Japan
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Fukuoka, 810-0001, Japan
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Fukuoka, 812-8582, Japan
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Kagawa, 761-0793, Japan
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Kashihara, 634-8522, Japan
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Kobe, 650-0017, Japan
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Kumamoto, 860-8556, Japan
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Kurume, 830-0011, Japan
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Matsumoto-shi, 390-8621, Japan
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Nagoya, 466-8560, Japan
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Nankoku, 783-0043, Japan
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Niigata, 951-8520, Japan
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Okayama, 700-8558, Japan
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Sapporo, 060-8543, Japan
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Sapporo, 060-8648, Japan
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Sendai, 980-8574, Japan
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Suita, 564-8565, Japan
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Tokyo, 160-8582, Japan
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Kajang, 43000, Malaysia
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Kuala Lumpur, 59100, Malaysia
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Eindhoven, 5623 EJ, Netherlands
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Groningen, 9713 GZ, Netherlands
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Maastricht, 6229 HX, Netherlands
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Rotterdam, 3015 GD, Netherlands
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Utrecht, 3584 CX, Netherlands
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Christchurch, 8011, New Zealand
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Hamilton, 3204, New Zealand
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Ålesund, 6017, Norway
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Lørenskog, 1478, Norway
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Carnaxide, 2790-134, Portugal
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Creixomil, 4835-044, Portugal
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Leiria, 2410-197, Portugal
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Lisbon, 1169-024, Portugal
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Lisbon, 1649-035, Portugal
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Vila Real, 5000-508, Portugal
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Viseu, 3504-509, Portugal
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Bucharest, 022328, Romania
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Cluj-Napoca, 400001, Romania
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Košice, 040 11, Slovakia
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Incheon, 22332, South Korea
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Seoul, 03080, South Korea
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Seoul, 03722, South Korea
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Seoul, 06351, South Korea
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Seoul, 06591, South Korea
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A Coruña, 15006, Spain
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Barcelona, 08035, Spain
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Barcelona, 08036, Spain
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Bilbao, 48013, Spain
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El Palmar, 30120, Spain
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Huelva, 21005, Spain
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Jaén, 23007, Spain
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L'Hospitalet de Llobregat, 8907, Spain
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Lleida, 25198, Spain
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Madrid, 28046, Spain
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Madrid, 28222, Spain
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Palma de Mallorca, 07198, Spain
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Pamplona, 31008, Spain
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Salamanca, 37007, Spain
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Santiago de Compostela, 15706, Spain
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Valencia, 46010, Spain
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Valencia, 46026, Spain
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Vigo, 36213, Spain
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Gothenburg, 413 45, Sweden
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Lund, 222 42, Sweden
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Solna, 171 76, Sweden
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Basel, 4051, Switzerland
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Geneva, 1205, Switzerland
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Lucerne, 6000, Switzerland
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Sankt Gallen, 9007, Switzerland
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New Taipei City, 220, Taiwan
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Taipei, 10002, Taiwan
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Taipei, 112, Taiwan
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Bellshill, ML4 3NJ, United Kingdom
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Birmingham, B15 2SQ, United Kingdom
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Cardiff, CF15 9SS, United Kingdom
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London, NW10 2PB, United Kingdom
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London, NW3 2QG, United Kingdom
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Manchester, M15 6SE, United Kingdom

Conditions

Explore the condition pages connected to this study.

TRANSTHYRETIN AMYLOIDOSIS WITH CARDIOMYOPATHY