Scans reveal if new drug clears deadly heart protein

NCT ID NCT06073587

Summary

This study uses special heart scans to see if an investigational drug, eplontersen, can reduce the buildup of a harmful protein in the heart. It involves up to 150 people who already have a heart condition called ATTR amyloidosis and are part of a larger drug trial. The main goal is to compare scan images from the start of the study to those taken after about 2.5 years of treatment to measure any change in the amount of protein in the heart.

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Contacts and locations

Locations

  • Cleveland Clinic Main Campus

    Cleveland, Ohio, 44195, United States

  • Columbia University Irving Medical Center

    New York, New York, 10032, United States

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • Hospital Universitario Puerta de Hierro

    Majadahonda, 28222, Spain

  • Oregon Health and Science University

    Portland, Oregon, 97239, United States

Conditions

Explore the condition pages connected to this study.