Healthy volunteers to test liquid Diet's gut effects
NCT ID NCT07426003
First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 2 times
Summary
This study will give 25 healthy adults a special liquid nutrition formula or a restricted diet of chicken, eggs, potatoes, bananas, and apples. Researchers will measure how fast food moves through the gut using a swallowed marker and X-rays. The goal is to understand how these diets affect digestion in people without gut disease.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Kate Farms Peptide 1.5 (a liquid nutrition formula) and a Crohn's disease exclusion diet (chicken, eggs, potatoes, bananas, apples)
- What this could lead to
- If successful, this study could help researchers understand how enteral nutrition works in the gut, which may guide future treatments for inflammatory bowel diseases.
- What could go wrong
- This is a small, early-stage study in healthy volunteers, not patients. It only measures digestion markers, not disease outcomes, so results may not apply to people with gut inflammation.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 25 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2026
- Expected to finish
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May 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Must be able to read and understand English 2. Must be able to sign a consent form for the study Exclusion Criteria: 1. BMI \<20 or \>30 2. Unintentional weight loss of \>10% in the last 3-6 months 3. Kidney disease 4. Diagnosis of cirrhosis 5. Taking diuretics 6. Anemia - Hemoglobin \<lower limit of normal in men or \<10 g/dL in women. 7. Taking iron supplements within 2 weeks for Visit 2.1 8. Taking prebiotic or probiotic supplements or any supplement including a multivitamin within 2 weeks of Visit 2.1 9. Taking antibiotics less than 4 weeks prior to Visit 2.1 10. Diarrhea in the 2 weeks prior to Visit 2.1 11. Diabetes mellitus 12. Diagnosis of congestive heart failure 13. Diagnosis of inflammatory bowel disease or celiac disease 14. Bowel resection other than an appendectomy 15. Pregnancy or breastfeeding 16. Intolerance or allergy to nutritional formula, chicken, eggs, apples, banana, potatoes 17. Using protein supplements, including powder added to food or drinks within 2 weeks of Visit 2.1 18. Baseline bowel frequency less than every 2 days or greater than 3 times daily 19. Student or employee of any one of the investigators. 20. Anyone who cannot receive study payment (e.g. visa constraints). 21. Any condition that the investigator feels may limit the volunteer's ability to complete the study protocol.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Penn Center for Advance Medicine, University of Pennsylvania
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States