Could a simple artery shot replace opioids for Post-Brain bleed headaches?
NCT ID NCT07054801
First seen Jun 25, 2026 · Last updated Jul 09, 2026 · Updated 4 times
Summary
This phase 2 trial tests whether injecting lidocaine and methylprednisolone into the middle meningeal artery can reduce severe headaches after a subarachnoid hemorrhage (a type of brain bleed). The procedure is done during a routine angiogram and aims to lower pain and opioid use. The study will enroll 25 adults with persistent headaches after SAH and track their pain scores for 12 weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- lidocaine and methylprednisolone
- What this could lead to
- If it works, this could offer a new way to relieve severe headaches after a brain bleed and reduce the need for opioid painkillers.
- What could go wrong
- This is a small, early-phase trial with only 25 participants, so results may not apply to everyone. The procedure carries risks like any artery injection, and the benefit is not yet proven.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of California, San Francisco
RECRUITINGSan Francisco, California, 94143, United States