New hope for advanced head and neck cancer patients in major phase 3 trial

NCT ID NCT06525220

Recruiting now Disease control Sponsor: Merus B.V. Source: ClinicalTrials.gov ↗

Summary

This study is testing whether adding a new drug called petosemtamab to standard pembrolizumab treatment works better for advanced head and neck cancer. It will involve about 500 adults whose cancer has returned or spread and who haven't had prior treatment for metastatic disease. The main goal is to see if the combination helps patients live longer and respond better to treatment compared to the standard drug alone.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Site 1
RECRUITING

Houston, Texas, 77030, United States
Site 10
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Salt Lake City, Utah, 84112, United States
Site 100
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Dresden, 01307, Germany
Site 101
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Le Mans, 72000, France
Site 102
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Cambridge, CB20QQ, United Kingdom
Site 103
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Kaohsiung City, 833, Taiwan
Site 104
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Hanover, 30625, Germany
Site 105
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Paris, 75005, France
Site 106
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Gliwice, 44-102, Poland
Site 107
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Pathum Wan, Bangkok, 10330, Thailand
Site 108
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Washington D.C., District of Columbia, 20010, United States
Site 109
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Liège, 4000, Belgium
Site 11
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Blacktown, New South Wales, 2148, Australia
Site 110
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Würzburg, 97080, Germany
Site 111
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Winnipeg, R3E0V9, Canada
Site 112
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Villejuif, 94800, France
Site 113
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Durham, North Carolina, 27710, United States
Site 114
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Bangkok Noi, Bangkok, 10700, Thailand
Site 115
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Memphis, Tennessee, 38103, United States
Site 116
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Krakow, 31-826, Poland
Site 117
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Heraklion, Crete, 715 00, Greece
Site 118
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Winston-Salem, North Carolina, 27157, United States
Site 119
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Pátrai, Achaia, 265 04, Greece
Site 12
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Blacksburg, Virginia, 24060, United States
Site 120
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Badalona, 08916, Spain
Site 121
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Münster, 48149, Germany
Site 122
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Milan, 20133, Italy
Site 123
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Kashiwa, Chiba, 277-8577, Japan
Site 124
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Chuo Ku, Tokyo, 104-0045, Japan
Site 125
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Ōsaka-sayama, Osaka, 589-8511, Japan
Site 126
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Sendai, Miyagi, 960-8574, Japan
Site 127
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Hiragi, Kagawa-ken, 761-0793, Japan
Site 128
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Madrid, 28040, Spain
Site 129
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Mannheim, 68167, Germany
Site 13
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Goyang-si, 10408, South Korea
Site 130
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Ulm, 89075, Germany
Site 131
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Gdansk, 80-214, Poland
Site 132
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London, EC1A 7BE, United Kingdom
Site 133
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Bonn, 53175, Germany
Site 134
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São Paulo, 01509-900, Brazil
Site 135
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Taunton, TA1 5DA, United Kingdom
Site 136
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São Paulo, 04538-132, Brazil
Site 137
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Recife, 50040-000, Brazil
Site 138
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Rio de Janeiro, 22281-100, Brazil
Site 139
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Meldola, 47014, Italy
Site 14
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Fort Myers, Florida, 33901, United States
Site 140
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Porto Alegre, 90610-000, Brazil
Site 141
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Belo Horizonte, 30.360-680, Brazil
Site 142
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Porto Alegre, 91350-200, Brazil
Site 143
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Paris, 75013, France
Site 144
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Natal, 59020-340, Brazil
Site 145
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Busan, 48108, South Korea
Site 146
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Chiang Rai, Changwat Chiang Rai, 57000, Thailand
Site 147
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Southampton, SO16 6YD, United Kingdom
Site 148
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München, 81675, Germany
Site 149
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Rio de Janeiro, Rio de Janeiro, 22.250-905, Brazil
Site 15
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Tyler, Texas, 75702, United States
Site 150
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Bydgoszcz, 85-796, Poland
Site 151
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Melbourne, Victoria, 3004, Australia
Site 152
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Naples, 80131, Italy
Site 153
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Philadelphia, Pennsylvania, 19107, United States
Site 154
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Philadelphia, Pennsylvania, 19114, United States
Site 155
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Minneapolis, Minnesota, 55417, United States
Site 156
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Athens, Attica, 151 23, Greece
Site 157
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Suwon, 16499, South Korea
Site 158
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Warsaw, 02-781, Poland
Site 159
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Kuching, 93586, Malaysia
Site 16
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Palo Alto, California, 94304, United States
Site 160
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Madrid, 28050, Spain
Site 161
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Putrajaya, 62250, Malaysia
Site 162
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Baton Rouge, Louisiana, 70809, United States
Site 163
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Johor Bahru, 81100, Malaysia
Site 164
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Mobile, Alabama, 36607, United States
Site 165
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St. John's, A1B3V6, Canada
Site 166
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Greenslopes, Queensland, 4120, Australia
Site 167
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Nagoya, Aichi-ken, 464-8681, Japan
Site 168
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St Louis, Missouri, 63108, United States
Site 169
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Cardiff, CF14 2TL, United Kingdom
Site 17
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Sugarland, Texas, 77479, United States
Site 170
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CABA, C1113AAE, Argentina
Site 171
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Atlanta, Georgia, 30322, United States
Site 172
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Coimbra, 3004-561, Portugal
Site 173
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Manchester, M20 4BX, United Kingdom
Site 174
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Natori-shi, Miyagi, 981-1293, Japan
Site 175
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Porto, 4200-072, Portugal
Site 176
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Antalya, 07025, Turkey (Türkiye)
Site 177
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Newcastle upon Tyne, NE7 7DN, United Kingdom
Site 178
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Dortmund, 44137, Germany
Site 179
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Vilnius, 08406, Lithuania
Site 18
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Plano, Texas, 75075, United States
Site 180
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Cagliari, 09121, Italy
Site 181
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Portimão, 8500-338, Portugal
Site 182
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Lisbon, 1998-018, Portugal
Site 183
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Kaunas, 50161, Lithuania
Site 184
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Ankara, 06230, Turkey (Türkiye)
Site 185
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Fukuoka, Fukuoka, 810-8563, Japan
Site 186
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Rome, 00161, Italy
Site 187
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Szeged, 6720, Hungary
Site 188
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Minato-Ku, Tokyo, 105-8471, Japan
Site 189
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Pécs, 7624, Hungary
Site 19
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Newark, Delaware, 19713, United States
Site 190
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Lodz, 93-513, Poland
Site 191
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Cleveland, Ohio, 44195, United States
Site 2
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Louisville, Kentucky, 40202, United States
Site 20
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West Palm Beach, Florida, 33401, United States
Site 21
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St. Petersburg, Florida, 33705, United States
Site 22
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Austin, Texas, 78745, United States
Site 23
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Norfolk, Virginia, 23502, United States
Site 24
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St Leonards, New South Wales, 2065, Australia
Site 25
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Temuco, 76281055-7, Chile
Site 26
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Providencia, 7500859, Chile
Site 27
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Los Angeles, California, 90033, United States
Site 28
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Seoul, 03722, South Korea
Site 29
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Recoleta, 8420000, Chile
Site 3
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Ramat Gan, 5266202, Israel
Site 30
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La Rioja, 5300, Argentina
Site 31
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Córdoba, X5008HHW, Argentina
Site 32
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Santiago, 7560908, Chile
Site 33
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Taipei, 112, Taiwan
Site 34
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Santiago, 8330336, Chile
Site 35
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Seoul, 03722, South Korea
Site 36
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La Jolla, California, 92037, United States
Site 37
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CABA, C1125ABD, Argentina
Site 38
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Antofagasta, 1263521, Chile
Site 39
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Taipei, 100, Taiwan
Site 4
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Kaohsiung City, 80756, Taiwan
Site 40
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Santiago, 7500921, Chile
Site 41
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Changhua, 500, Taiwan
Site 42
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Suwon, 16247, South Korea
Site 43
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Philadelphia, Pennsylvania, 19104, United States
Site 44
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Toronto, M5G 2M9, Canada
Site 45
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Seoul, 05505, South Korea
Site 46
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Viedma, R8500ACE, Argentina
Site 47
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Gyeonggi-do, 13496, South Korea
Site 48
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Orlando, Florida, 32804, United States
Site 49
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Taoyuan, 333, Taiwan
Site 5
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Jerusalem, 9112001, Israel
Site 50
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Chicago, Illinois, 60637, United States
Site 51
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Hwasun, 58128, South Korea
Site 52
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Taichung, 40447, Taiwan
Site 53
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Brussels, 1200, Belgium
Site 54
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Rouen, 76038, France
Site 55
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Montpellier, 34298, France
Site 56
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Bordeaux, 33075, France
Site 57
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Marseille, 13005, France
Site 58
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Nijmegen, 6525 GA, Netherlands
Site 59
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Toulouse, 31100, France
Site 6
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Albuquerque, New Mexico, 87131, United States
Site 60
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Greifswald, 17475, Germany
Site 61
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Pamplona, 31008, Spain
Site 62
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Pamplona, 31008, Spain
Site 63
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Namur, 5000, Belgium
Site 64
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Vandœuvre-lès-Nancy, 54519, France
Site 65
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Ratchathewi, Bangkok, 10400, Thailand
Site 66
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Nice, 06189, France
Site 67
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Madrid, 28041, Spain
Site 68
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Utrecht, 3584 CX, Netherlands
Site 69
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London, SW3 6JJ, United Kingdom
Site 7
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Tel Aviv, 6423906, Israel
Site 70
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Sutton, SM2 5PT, United Kingdom
Site 71
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Leuven, 3000, Belgium
Site 72
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Lyon, 69378, France
Site 73
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Marbella, 29660, Spain
Site 74
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Valencia, 46009, Spain
Site 75
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Madrid, 28040, Spain
Site 76
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Rosario, S2000KZE, Argentina
Site 77
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Hat Yai, Changwat Songkhla, 90110, Thailand
Site 78
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Tübingen, 72076, Germany
Site 79
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Lille, 59000, France
Site 8
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Orlando, Florida, 32827, United States
Site 80
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Barcelona, 08035, Spain
Site 81
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Milan, 20141, Italy
Site 82
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Hamburg, 20251, Germany
Site 83
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Northwood, HA62RN, United Kingdom
Site 84
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Amsterdam, 1066 CX, Netherlands
Site 85
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Rozzano, 20089, Italy
Site 86
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Ancona, 60126, Italy
Site 87
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Poitiers, 86021, France
Site 88
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Nashville, Tennessee, 37203, United States
Site 89
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Chattanooga, Tennessee, 37404, United States
Site 9
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Haifa, 3109601, Israel
Site 90
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London, SE19RT, United Kingdom
Site 91
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Hamburg, 22763, Germany
Site 92
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Panórama, 55236, Greece
Site 93
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Naples, 80131, Italy
Site 94
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Hackensack, New Jersey, 07601, United States
Site 95
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Chaïdári, 12462, Greece
Site 96
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CABA, C1118AAT, Argentina
Site 97
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Brescia, 25123, Italy
Site 98
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Edegem, 2650, Belgium
Site 99
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Ghent, 9000, Belgium

Conditions

Explore the condition pages connected to this study.

HEAD AND NECK SQUAMOUS CELL CARCINOMA