New cancer injection trial offers hope for elderly patients ineligible for standard chemo

NCT ID NCT04892173

Recruiting now Disease control Sponsor: Johnson & Johnson Enterprise Innovation Inc. Source: ClinicalTrials.gov ↗

Summary

This study is testing whether adding a new nanoparticle injection (NBTXR3) to standard radiation therapy works better for controlling advanced head and neck cancer in elderly patients. It is for people aged 60 and older who cannot safely receive the usual platinum-based chemotherapy. The main goal is to see if this new combination helps patients live longer without their cancer getting worse.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

AdventHealth Orlando
RECRUITING

Orlando, Florida, 32803, United States
Aichi Cancer Center
RECRUITING

Nagoya, 464-8681, Japan
Apollo Speciality Hospital, Chennai
COMPLETED

Chennai, 600035, India
Asan Medical Center
RECRUITING

Seoul, 05505, South Korea
Associacao Feminina de Educacao e Combate ao Cancer Hospital Santa Rita de Cassia
RECRUITING

Vitória, 29043 260, Brazil
Athens Medical Center S A Interbalkan Medical Center of Thessaloniki
RECRUITING

Thessaloniki, 54639, Greece
Atrium Health Levine Cancer Institute
RECRUITING

Charlotte, North Carolina, 28204, United States
Boston Medical Center
RECRUITING

Boston, Massachusetts, 02118, United States
CHU Amiens Picardie
RECRUITING

Amiens, 80000, France
CHU Brest
RECRUITING

Brest, 29609, France
CHU Saint Etienne
RECRUITING

Saint-Etienne, 42055, France
CLCC - Centre Henri Becquerel
RECRUITING

Rouen, 76038, France
Centre Francois Baclesse
RECRUITING

Caen, 14076, France
Centre Georges Francois Leclerc
RECRUITING

Dijon, 21000, France
Centre Hospitalier de Valenciennes Hopital Jean Bernard
COMPLETED

Valenciennes, 59322, France
Centre Leon Berard
COMPLETED

Lyon, 69008, France
Centre de Lutte contre le Cancer Centre Oscar Lambret
RECRUITING

Lille, 59020, France
Centro Regional Integrado de Oncologia CRIO
RECRUITING

Fortaleza, 60336 232, Brazil
Chang-Gung Memorial Hospital-Keelung
RECRUITING

Keelung, 20442, Taiwan
Changhua Christian Hospital
RECRUITING

Changhua, 500, Taiwan
Christus St. Vincent Regional Cancer Center
COMPLETED

Santa Fe, New Mexico, 87505, United States
City of Hope
RECRUITING

Duarte, California, 91010, United States
Clinique Ambroise Pare
COMPLETED

Neuilly-sur-Seine, 92200, France
Cliniques Universitaires Saint Luc
RECRUITING

Brussels, 1200, Belgium
Dongguan People s Hospital
RECRUITING

Dongguan, 523109, China
Emory University Hospital Midtown
RECRUITING

Atlanta, Georgia, 30308, United States
Ensino e Terapia de Inovacao Clinica AMO Etica
RECRUITING

Salvador, 41950 640, Brazil
Eszak Pesti Centrumkorhaz Honvedkorhaz
COMPLETED

Budapest, 1062, Hungary
Fakultni nemocnice Olomouc
COMPLETED

Olomouc, 779 00, Czechia
Fudan University Shanghai Cancer Center
COMPLETED

Shanghai, 200032, China
Fujian Medical University Fujian Provincial Cancer Hospital
RECRUITING

Fuzhou, 350014, China
Fujian Medical University Union Hospital
COMPLETED

Fuzhou, 350001, China
Fundacao Faculdade de Medicina - Instituto do Cancer do Estado de Sao Paulo
RECRUITING

São Paulo, 01246 000, Brazil
Fundacao Pio Xii - Hospital De Cancer De Barretos
RECRUITING

Barretos, 14784, Brazil
Fundacao Sao Francisco Xavier
RECRUITING

Ipatinga, 35160 158, Brazil
George Washington University Cancer Center
RECRUITING

Washington D.C., District of Columbia, 20052, United States
Grand Hopital De Charleroi Site Les Viviers
RECRUITING

Charleroi, 6060, Belgium
Grant Medical foundation Ruby Hall Clinic
COMPLETED

Pune, 411 001, India
Grupo Oncoclinicas - Botafogo
RECRUITING

Rio de Janeiro, 22250-905, Brazil
Guangzhou First Municipal People's Hospital
RECRUITING

Guangzhou, 510180, China
Guangzhou Medical University Affiliated Oncology Hospital
RECRUITING

Guangzhou, 510095, China
Gustave Roussy
RECRUITING

Villejuif, 94805, France
Hadassah Medical Center
COMPLETED

Jerusalem, 9112001, Israel
HealthCare Global HCG Manavata Cancer Centre
RECRUITING

Nashik, 422002, India
Henan Cancer Hospital
COMPLETED

Zhengzhou, 450008, China
Herbert Irving Comprehensive Cancer Center Columbia University Medical Center
COMPLETED

New York, New York, 10032, United States
High Technology Hospital MedCenter Ltd Batumi
RECRUITING

Batumi, 6000, Georgia
Hiroshima University Hospital
RECRUITING

Hiroshima, 734 8551, Japan
Hoag Memorial Hospital
RECRUITING

Newport Beach, California, 92663, United States
Hopital Europeen Georges Pompidou
RECRUITING

Paris, 75015, France
Hopital Haut Leveque
RECRUITING

Pessac, 33604, France
Hopital Pontchaillou
RECRUITING

Rennes, 35000, France
Hopital Tenon
RECRUITING

Paris, 75970, France
Hopital de la Timone
RECRUITING

Marseille, 13385, France
Hosp Clinic de Barcelona
COMPLETED

Barcelona, 08036, Spain
Hosp Regional Univ de Malaga
RECRUITING

Málaga, 29010, Spain
Hosp Univ Fund Jimenez Diaz
RECRUITING

Madrid, 28040, Spain
Hosp Univ Hm Sanchinarro
RECRUITING

Madrid, 28050, Spain
Hosp Univ Vall D Hebron
RECRUITING

Barcelona, 8035, Spain
Hosp. Clinico Univ. Lozano Blesa
RECRUITING

Zaragoza, 50009, Spain
Hosp. Cuf Descobertas
RECRUITING

Lisbon, 1998050, Portugal
Hosp. Gral. Univ. Gregorio Maranon
RECRUITING

Madrid, 28007, Spain
Hosp. Gral. Univ. Valencia
RECRUITING

Valencia, 46014, Spain
Hosp. Univ. 12 de Octubre
RECRUITING

Madrid, 28041, Spain
Hosp. Univ. Lucus Augusti
RECRUITING

Lugo, 27003, Spain
Hosp. Univ. Marques de Valdecilla
RECRUITING

Santander, 39008, Spain
Hosp. Univ. de Cruces
RECRUITING

Barakaldo, 48903, Spain
Hosp. Virgen Del Rocio
RECRUITING

Seville, 41013, Spain
Hosp. de Navarra
COMPLETED

Pamplona, 31008, Spain
Hospital Amaral Carvalho
RECRUITING

Jaú, 17210120, Brazil
Hospital Haroldo Juaçaba - Instituto do Câncer do Ceará
RECRUITING

Fortaleza, 60430-230, Brazil
Hospital Nossa Senhora da Conceicao
COMPLETED

Porto Alegre, 91350-200, Brazil
Hospital Sao Lucas da PUCRS
RECRUITING

Porto Alegre, 90610-000, Brazil
Hospital Sirio Libanes Sao Paulo
RECRUITING

São Paulo, 01308-050, Brazil
Hospital de Base de Sao Jose do Rio Preto
RECRUITING

São José do Rio Preto, 15090-000, Brazil
Hospital do Cancer de Londrina
RECRUITING

Londrina, 86015 520, Brazil
Hospitales Universitarios San Roque En Las Palmas de Gran Canaria Centro Oncologico Integral Canario
COMPLETED

Las Palmas de Gran Canaria, 35001, Spain
Hubei Cancer Hospital
RECRUITING

Wuhan, 430079, China
Hunan Cancer hospital
RECRUITING

Changsha, 410013, China
Inst. Valenciano de Oncologia
RECRUITING

Valencia, 46009, Spain
Institut Curie
RECRUITING

Paris, 75248, France
Institut de Cancerologie de Lorraine
RECRUITING

Vandœuvre-lès-Nancy, 54500, France
Institute of Oncology and Radiology of Serbia
COMPLETED

Belgrade, 11000, Serbia
Institute of Oncology of Vojvodina
COMPLETED

Kamenitz, 21204, Serbia
Instituto Catalan Deoncologia Hospital Duran I Reynals
RECRUITING

L'Hospitalet de Llobregat, 08908, Spain
Institutul Oncologic Prof Dr Al Trestioreanu Bucuresti
RECRUITING

Bucharest, 22328, Romania
Interbalkan Medical Center of Thessaloniki
COMPLETED

Thessaloniki, 57001, Greece
Irmandade da Santa Casa de Misericordia de Porto Alegre
RECRUITING

Porto Alegre, 90050-170, Brazil
JSC Vian Kutaisi Referral Hospital
RECRUITING

Kutaisi, 4600, Georgia
Jiangsu Cancer Hospital
COMPLETED

Nanjing, 210009, China
Jiangxi Cancer Hospital
COMPLETED

Nanchang, 330029, China
Jichi Medical University Hospital
RECRUITING

Shimotsuke, 329-0498, Japan
Kindai University Hospital
COMPLETED

Osaka Sayama Shi, 589 8511, Japan
Klinicki bolnicki centar Zagreb
COMPLETED

Zagreb, 10000, Croatia
Klinikum rechts der Isar an der Technischen Universitat Munchen
COMPLETED

München, 81675, Germany
Liaoning Cancer Hospital and Institute
COMPLETED

Shenyang, 110042, China
Linyi Cancer Hospital
RECRUITING

Linyi, 276002, China
Liuzhou people's Hospital
RECRUITING

Liuchow, 545006, China
Ltd Tbilisi State Medical University and Ingorokva High Medical Technology University Clinic
RECRUITING

Tbilisi, 144, Georgia
M S Ramaiah Memorial Hospital
RECRUITING

Bangalore, 560054, India
MHAT Uni Hospital
COMPLETED

Panagyurishte, 4500, Bulgaria
Macon Joan Brock Virginia Health Sciences Eastern Virginia Medical Group at Old Dominion University
RECRUITING

Norfolk, Virginia, 23507, United States
Manila Doctors Hospital
RECRUITING

Manila, 1000, Philippines
Mayo Clinic Jacksonville
RECRUITING

Jacksonville, Florida, 32224, United States
Medizinische Hochschule Hannover
RECRUITING

Hanover, 30625, Germany
Medizinische Universitaet Wien
RECRUITING

Vienna, 1090, Austria
Medizinische Universitat Graz
COMPLETED

Graz, 8036, Austria
Meenakshi Mission Hospital and Research Center
COMPLETED

Madurai, 625107, India
Memorial Radiation Oncology Medical Group Laguna Hills
COMPLETED

Laguna Hills, California, 92653, United States
Moffitt Cancer Center
RECRUITING

Tampa, Florida, 33612, United States
Montefiore Medical Center
RECRUITING

The Bronx, New York, 10467, United States
NHS Greater Glasgow and Clyde
RECRUITING

Glasgow, G12 0YN, United Kingdom
Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School
RECRUITING

Nanjing, 223800, China
National Cancer Center Hospital East
RECRUITING

Kashiwa, 277-8577, Japan
National Cheng Kung University Hospital
RECRUITING

Bei Qu, 704, Taiwan
National Taiwan University Hospital
RECRUITING

Taipei, 100, Taiwan
Nemocnice Bulovka
COMPLETED

Prague, 180 81, Czechia
Newcastle upon Tyne Hospitals NHS Foundation Trust
RECRUITING

Newcastle upon Tyne, NE7 7DN, United Kingdom
Nucleo de Ensino e Pesquisa do Instituto Mario Penna
RECRUITING

Belo Horizonte, 30380 472, Brazil
Ordensklinikum Linz GmbH Barmherzige Schwestern
RECRUITING

Linz, 4010, Austria
Oregon Health And Science University
RECRUITING

Portland, Oregon, 97239, United States
Orszagos Onkologiai Intezet
RECRUITING

Budapest, 1122, Hungary
Osaka International Cancer Institute
RECRUITING

Osaka, 541 8567, Japan
Peking University Shenzhen Hospital
RECRUITING

Shenzhen, 518036, China
Qilu Hospital of Shandong University
RECRUITING

Jinan, 250012, China
Rambam Health Care Campus
COMPLETED

Haifa, 3109601, Israel
Richmond University Medical Center
RECRUITING

Staten Island, New York, 10310, United States
Sahlgrenska Universitetssjukhuset
COMPLETED

Gothenburg, 41345, Sweden
Samson Assuta Ashdod University Hospital
COMPLETED

Ashdod, 7747629, Israel
Second Affiliated Hospital, SooChow University
COMPLETED

Suzhou, 215004, China
Severance Hospital Yonsei University Health System
RECRUITING

Seoul, 03722, South Korea
Shandong Cancer Hospital
RECRUITING

Jinan, 250117, China
Shanxi Provincial Cancer hospital
COMPLETED

Taiyuan, 30013, China
Shizuoka Cancer Center
RECRUITING

Sunto Gun, 411 8777, Japan
Sichuan Cancer Hospital
RECRUITING

Chengdu, 610041, China
Specialized Hospital for Active Treatment in Oncology
COMPLETED

Sofia, 1756, Bulgaria
St. Luke's Medical Center
RECRUITING

Quezon City, 1112, Philippines
Stephenson Cancer Center
RECRUITING

Oklahoma City, Oklahoma, 73104, United States
Sunnybrook Health Sciences Center
RECRUITING

Toronto, Ontario, M4N 3M5, Canada
Szent Gyorgyi Albert Klinikai Kozpont Onkoterapias Klinika
RECRUITING

Szeged, 6720, Hungary
Taichung Veterans General Hospital
RECRUITING

Taichung, 40705, Taiwan
Tampereen Yliopistollinen Sairaala
COMPLETED

Tampere, 33520, Finland
Tata Memorial Hospital
RECRUITING

Mumbai, 400012, India
Tel Aviv Sourasky Medical Center
COMPLETED

Tel Aviv, 6423906, Israel
The Affiliated Hospital of Bengbu Medical College
COMPLETED

Bengbu, 233004, China
The Affiliated Hospital of Medical College Qingdao University
RECRUITING

Qingdao, 266003, China
The Affiliated Hospital of Xuzhou Medical University
COMPLETED

Xuzhou, 221000, China
The Cancer Hospital Affiliated to Guangxi Medical University
RECRUITING

Nanning, 530021, China
The Catholic University of Korea Seoul St Mary s Hospital
RECRUITING

Seoul, 06591, South Korea
The Catholic university of Korea, St. Vincent's Hospital
RECRUITING

Suwon, 16247, South Korea
The Fifth Affiliated Hospital Sun Yat Sen University
RECRUITING

Zhuhai, 519000, China
The First Affiliated Hospital of Fujian Medical University
RECRUITING

Fuzhou, 350005, China
The First Affiliated Hospital of Guangdong Pharmaceutical University
RECRUITING

Guangzhou, 510080, China
The Fourth Hospital of Hebei Medical University
RECRUITING

Shijiazhuang, 50011, China
The Medical City
RECRUITING

Pasig, 1600, Philippines
The Royal Marsden NHS Foundation Trust
RECRUITING

London, SW3 6JJ, United Kingdom
The Royal Surrey County Hospital NHS Foundation Trust
RECRUITING

Guildford, GU2 7XX, United Kingdom
The first affiliated hospital of xiamen university
COMPLETED

Xiamen, 361003, China
Tianjin Medical University Cancer Institute and Hospital
COMPLETED

Tianjin, 300060, China
Todua Clinic
COMPLETED

Tbilisi, 0112, Georgia
Tohoku University Hospital
RECRUITING

Sendai, 980 8574, Japan
Tokyo Medical University Hospital
RECRUITING

Shinjuku, 160 0023, Japan
Tokyo Medical and Dental University Hospital
RECRUITING

Bunkyō City, 113-8519, Japan
Tongji Hospital Tongji Medical College of Huazhong University of Science and Technology
RECRUITING

Wuhan, 430030, China
UCLA Hematology Oncology
RECRUITING

Los Angeles, California, 90095, United States
Uls Braga - Hosp. Braga
COMPLETED

Braga, 4710 243, Portugal
Uls Gaia Espinho
RECRUITING

Vila Nova de Gaia, 4434 502, Portugal
Uls Santa Maria - Hosp. Santa Maria
COMPLETED

Lisbon, 1649 035, Portugal
Uls Santo Antonio - Hosp. Santo Antonio
COMPLETED

Porto, 4099-001, Portugal
Union Hospital Tongji Medical College of Huazhong University of Science and Technology
RECRUITING

Wuhan, 430022, China
Universitaetsklinikum Giessen und Marburg GmbH
RECRUITING

Giessen, 35392, Germany
Universitaetsmedizin Rostock
RECRUITING

Rostock, 18059, Germany
Universitair Ziekenhuis Leuven
RECRUITING

Leuven, 3000, Belgium
Universitatsklinikum Jena
RECRUITING

Jena, 07747, Germany
University Clinical Center Kragujevac
COMPLETED

Kragujevac, 34000, Serbia
University General Hospital Attikon General Hospital Of West Attica H Agia Varvara
RECRUITING

Athens, 124 62, Greece
University Hospital Of Larissa
RECRUITING

Larissa, 41110, Greece
University of Alabama at Birmingham
RECRUITING

Birmingham, Alabama, 35294, United States
University of California San Francisco
RECRUITING

San Francisco, California, 94158, United States
University of California at San Diego Moores Cancer Center
RECRUITING

La Jolla, California, 92093, United States
University of Cincinnati
RECRUITING

Cincinnati, Ohio, 45219, United States
University of Kentucky Markey Cancer Center
RECRUITING

Lexington, Kentucky, 40536, United States
University of North Carolina at Chapel Hill
RECRUITING

Chapel Hill, North Carolina, 27514, United States
University of Pennsylvania Perelman Center for Advanced Medicine
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
University of Perpetual Help Dalta Medical Center, Inc
RECRUITING

Las Piñas, 1742, Philippines
University of Virginia
RECRUITING

Charlottesville, Virginia, 22908, United States
Vojnomedicinska Akademija
COMPLETED

Belgrade, 11000, Serbia
Wuming Hospital of Guangxi Medical University
RECRUITING

Nanning, 530000, China
Xiangya Hospital Central South University
COMPLETED

Changsha, 410008, China

Conditions

Explore the condition pages connected to this study.

AGED LOCALLY ADVANCED HEAD AND NECK SQUAMOUS CELL CARCINOMA