New combo therapy tested in battle against tough head & neck cancers

NCT ID NCT04811027

Summary

This study tested whether adding a new immunotherapy drug (eftilagimod alpha) to a standard treatment (pembrolizumab) works better for people with advanced head and neck cancer that has spread or returned. It involved 171 participants who had not yet received treatment for their advanced cancer. The goal was to see if the two-drug combination was safer and more effective at shrinking tumors and helping patients live longer.

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Contacts and locations

Locations

  • AZ Nikolaas

    Sint-Niklaas, 9100, Belgium

  • AZ Sint-Jan Brugge

    Bruges, 8000, Belgium

  • Antwerp University Hospital

    Edegem, 2650, Belgium

  • Arensia Exploratory Medicine Llc

    Kapitanivka, AL, 08112, Ukraine

  • Centre Hospitalier Universitaire (CHU) de Liege

    Liège, 4000, Belgium

  • Herlev Hospital

    Herlev, 2700, Denmark

  • Hospital 12 Octubre

    Madrid, 28041, Spain

  • Hospital Universitario Lucus Augusti

    Lugo, 27003, Spain

  • Hospital Universitario Miguel Servet

    Zaragoza, 50009, Spain

  • Hospital Universitario Ramón y Cajal

    Madrid, 28034, Spain

  • Hospital de la Santa Creu i de Sant Pau

    Barcelona, 08041, Spain

  • Institut Català d'Oncologia - Hospital Universitari de Girona

    Girona, 17007, Spain

  • Institute of Cancer Science - Beatson West of Scotland Cancer Centre

    Glasgow, 1053, United Kingdom

  • Macquarie University Hospital

    Macquarie Park, New South Wales, 2109, Australia

  • Nationales Centrum für Tumorerkrankungen Heidelberg

    Heidelberg, 69120, Germany

  • Nottingham University Hospitals, NHS Trust

    Nottingham, NG5 1PB, United Kingdom

  • Oncology Consultants

    Houston, Texas, 77030, United States

  • Rigshospitalet

    Copenhagen, 2100, Denmark

  • START Madrid (Hospital Universitario Fundación Jiménez Díaz)

    Madrid, 28040, Spain

  • The Christie NHS Foundation Trust

    Manchester, M20 4BX, United Kingdom

  • The Oncology Institute "Prof Dr Ion Chiricuta" I.O.C.N.

    Cluj-Napoca, 400015, Romania

  • University College London Hospitals NHS Foundation - The Harley Street Clinic

    London, NW1 2PG, United Kingdom

  • University Hospital Essen

    Essen, 45147, Germany

  • University of Alabama at Birmingham (UAB) - O'Neal Cancer Center

    Birmingham, Alabama, 35249, United States

  • Universitätsklinikum Bonn

    Bonn, North Rhine-Westphalia, 53127, Germany

  • Universitätsklinikum Ulm

    Ulm, 89075, Germany

  • Vall d'Hebron Institute of Oncology (VHIO)

    Barcelona, 08035, Spain

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.