New weapon added to fight aggressive head & neck cancer after surgery

NCT ID NCT03480672

Summary

This study tested if adding a newer immunotherapy drug (pembrolizumab) to the standard post-surgery treatment (chemotherapy plus radiation) works better for patients with high-risk head and neck cancer. It involved 211 patients who had surgery but were at high risk of the cancer returning. The main goal was to see if the new combination helped patients live longer without their cancer coming back.

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Contacts and locations

Locations

  • Charité - Universitätsmedizin Berlin; Klinik für Radioonkologie und Strahlentherapie CVK

    Berlin, Germany

  • Charité - Universitätsmedizin, CVK und CCM, Klinik für Hals-Nasen-Ohrenheilkunde

    Berlin, Germany

  • Department of Head Medicine and Oral Health, University of Leipzig

    Leipzig, 04103, Germany

  • Ernst von Bergmann Klinikum Potsdam, Zentrum für Hämatologie, Onkologie und Strahlenheilkunde, Klinik für Hämatologie und

    Potsdam, Germany

  • Helios Klinikum Erfurt GmbH, Klinik für Hals-Nasen-Ohrenheilkunde

    Erfurt, Germany

  • Kath. Marienkrankenhaus gGmbH, Zentrum für Innere Medizin Hämatologie/Onkologie

    Hamburg, Germany

  • Klinikum Bielefeld, Onkologie/Hämatologie/ Palliativmedizin

    Bielefeld, Germany

  • Klinikum Stuttgart - Katharinenhospital, Klinik für Radioonkologie und Strahlentherapie

    Stuttgart, Germany

  • UNIVERSITÄTSKLINIKUM Schleswig-Holstein, Campus Lübeck

    Lübeck, Germany

  • Universitätsklinikum Bonn; Med. Klinik III / ZIM, Hämatologie/Onkologie

    Bonn, Germany

  • Universitätsklinikum Düsseldorf, Klinik für Strahlentherapie und Radiologische Onkologie

    Düsseldorf, Germany

  • Universitätsklinikum Essen, Klinik und Poliklinik für Strahlentherapie

    Essen, Germany

  • Universitätsklinikum Jena, Klinik für Hals-Nasen-Ohrenheilkunde

    Jena, Germany

  • Universitätsklinikum Mannheim, Hals-Nasen-Ohren Klinik

    Mannheim, Germany

  • Universitätsklinikum Regensburg, Klinik und Poliklinik für Strahlentherapie

    Regensburg, Germany

  • Universitätsklinikum Würzburg; Klinik und Poliklinik für Strahlentherapie

    Würzburg, Germany

Conditions

Explore the condition pages connected to this study.