New combo therapy aims to extend lives in tough cancer recurrence

NCT ID NCT07026474

Recruiting now Disease control Sponsor: Universität des Saarlandes Source: ClinicalTrials.gov ↗

First seen Jan 05, 2026 · Last updated Apr 18, 2026 · Updated 15 times

Summary

This study is for adults whose head and neck cancer has returned locally after previous radiation treatment. It compares two approaches: one group gets a repeat course of radiation with chemotherapy followed by immunotherapy (pembrolizumab), while the other gets the standard immunotherapy with or without chemotherapy. The main goal is to see if the more intensive sequence helps people live longer.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for RECURRENT HEAD AND NECK SQUAMOUS CELL CARCINOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

CaritasKlinikum Saarbrücken St. Theresia, Klinik für Radioonkologie und Strahlentherapie
NOT_YET_RECRUITING

Saarbrücken, 66113, Germany
Gemeinschaftspraxis Hämatologie-Onkologie Dresden
RECRUITING

Dresden, 01307, Germany
Klinikum Chemnitz gGmbH, Klinik für Radioonkologie
RECRUITING

Chemnitz, 09116, Germany
Klinikum Darmstadt GmbH, Institut für Radioonkologie und Strahlentherapie
RECRUITING

Darmstadt, 64283, Germany
Klinikum St.-Elisabeth Straubing GmbH, Klinik für Hals-Nasen-Ohren-Heilkunde
NOT_YET_RECRUITING

Straubing, 94315, Germany
Klinikum Stuttgart, Klinik für Strahlentherapie und Radioonkologie
RECRUITING

Stuttgart, 70174, Germany
Marien Hospital Herne, Klinik für Strahlentherapie und Radio-Onkologie
RECRUITING

Herne, 44625, Germany
Medizinische Hochschule Hannover (MHH), Klinik für Hämatologie, Hämostaseologie, Onkologie und Stammzelltransplantation
NOT_YET_RECRUITING

Hanover, 30625, Germany
UKGM Gießen, Klinik für Strahlentherapie
RECRUITING

Giessen, 35392, Germany
Uniklinikum Erlangen, Strahlenklinik
RECRUITING

Erlangen, 91054, Germany
Universitätsklinikum Hamburg-Eppendorf, Zentrum für Onkologie; II. Medizinische Klinik und Poliklinik
NOT_YET_RECRUITING

Hamburg, 20246, Germany
Universitätsklinikum Münster, Klinik für Strahlentherapie - Radioonkologie
NOT_YET_RECRUITING

Münster, 48149, Germany
Universitätsklinikum Regensburg, Klinik und Poliklinik für Strahlentherapie
RECRUITING

Regensburg, 93053, Germany
Universitätsklinikum Tübingen, Klinik für Radioonkologie
RECRUITING

Tübingen, 72076, Germany
Universitätsklinikum Ulm, Klinik für Hals- Nasen-Ohrenheilkunde, Kopf- und Halschirurgie
RECRUITING

Ulm, 89075, Germany
Universitätsklinikum des Saarlandes, Klinik für Strahlentherapie und Radioonkologie
RECRUITING

Homburg, 66421, Germany
Universitätsmedizin Frankfurt, Klinik für Strahlentherapie und Onkologie
RECRUITING

Frankfurt am Main, 60590, Germany
Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Klinik und Poliklinik für Radioonkologie der Strahlentherapie
RECRUITING

Mainz, 55131, Germany

Conditions

Explore the condition pages connected to this study.

RECURRENT HEAD AND NECK SQUAMOUS CELL CARCINOMA