New lung cancer drug HB0025 faces off against standard therapy in major trial

NCT ID NCT07383116

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 3 trial will test whether a new drug called HB0025, combined with standard chemotherapy, works better than the current treatment tislelizumab plus chemotherapy for people with advanced nonsquamous non-small cell lung cancer. About 500 participants will be randomly assigned to one of the two treatment groups. The main goal is to see how long the cancer stays under control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

HB0025 injection (a new drug) combined with chemotherapy (pemetrexed plus carboplatin or cisplatin)

What this could lead to

If successful, this could offer a new first-line treatment option for people with advanced nonsquamous non-small cell lung cancer, potentially improving how long the cancer is kept under control.

What could go wrong

This is an early-stage Phase 3 trial that hasn't started recruiting yet. The new drug HB0025 may not be more effective than the existing treatment tislelizumab, and side effects from the combination are unknown.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The East Hospital Affiliated to Tongji University

    Shanghai, Shanghai 200120, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••