Half-Matched stem cell transplant offers new hope for rare blood diseases
NCT ID NCT03520647
First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 24 times
Summary
This study tests a stem cell transplant using blood stem cells from a half-matched family donor (like a parent or sibling) for people with severe aplastic anemia, a related bone marrow disorder, or a rare blood disease called PNH. Participants receive chemotherapy and a one-time radiation treatment before the transplant to prepare their body. The goal is to see if this approach helps people live longer without developing chronic graft-versus-host disease, a common complication where donor cells attack the body. The study involves 56 recipients aged 4 to 60 and their donors aged 4 to 75.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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