New DNA shots aim to stop deadly rodent virus

NCT ID NCT04333459

First seen May 29, 2026 · Last updated May 30, 2026 · Updated 1 time

Summary

This study tested two DNA vaccines designed to prevent hemorrhagic fever with renal syndrome caused by Hantaan and Puumala viruses. Healthy adults aged 18-49 received up to four doses via a needle-free jet injector. The goal was to see if the vaccines trigger a strong immune response and if a lower dose works as well as a higher one.

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Contacts and locations

Locations

  • Clinical Trials Center, Walter Reed Army Institute of Reserach

    Silver Spring, Maryland, 20910, United States

  • Department of Clinical Trials, WRAIR

    Silver Spring, Maryland, 20910, United States

Conditions

Explore the condition pages connected to this study.