Needle-Free DNA vaccines aim to stop deadly Rodent-Borne viruses

NCT ID NCT04333459

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two DNA vaccines designed to prevent hemorrhagic fever with renal syndrome caused by Hantaan and Puumala viruses. A total of 132 healthy adults received up to four doses of vaccine using a needle-free jet injector. The main goal was to see if the vaccines triggered a strong immune response, especially at a lower dose for the Hantaan vaccine.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Clinical Trials Center, Walter Reed Army Institute of Reserach

    Silver Spring, Maryland, 20910, United States

  • Department of Clinical Trials, WRAIR

    Silver Spring, Maryland, 20910, United States